Investigation of B lymphocytes: adhesion, motility and Ig class switching

In mammals, B lymphocytes produce antibodies to foreign antigens, such as virus, bacteria and fungus. When the body is exposed to such antigens, B cells respond by becoming activated to high-rate antibody secreting plasma cells. The immune reactions take place in the secondary lymphoid organs, for example lymph nodes and spleen. In these organs, B cells get signals by antigen, T cells and dendritic cells. Activated B cells form so-called germinal centres, consisting of rapidly proliferating cells.


Cell Biology  Per Ljungdahl, Phone: +46 8 16 41 01

Developmental Biology Christos Samakovlis, Phone: + 46 8 16 15 64

Immunology Marita Troye Blomberg, Phone: + 46 8 16 41 64

Physiology Barbara Cannon, Phone:+ 46 8 16 41 20


Imaging Facility, IFSU

Zeiss LSM 780