Carmen Fernández

Prof. Carmen Fernández

Stockholm University
The Wenner-Gren Institute
Immunology
Svante Arrheniusväg 20B, room F 554
106 91 Stockholm
Sweden

Email: carmen.fernandez@imun.su.se
Phone: 00 46 8 16 45 99
Fax: 00 46 8 612 95 42

Tuberculosis

The innate immune system in Mycobacterium infection.


The innate immune system provides an early response against invading microorganisms while the adaptive immune system operates at later stages when the pathogen has infected the host. In the first hours of exposure to and invasion by the pathogen, two outcomes can be schematically described: rejection/destruction of the pathogen (by innate immunity) and infection of the host (despite innate immunity).

Selected publications

A recombinant Bacille Calmette-Guérin construct expressing the Plasmodium falciparum circumsporozoite protein enhances dendritic cell activation and primes for circumsporozoite-specific memory cells in BALB/c mice.
Arama C, Waseem S, Fernández C, Assefaw-Redda Y, You L, Rodriguez A, Radošević K, Goudsmit J, Kaufmann SH, Reece ST, Troye-Blomberg M.
Vaccine. 2011 Oct 5. PMID: 21983157
 
Impact of toll-like receptor 2 deficiency on immune responses to mycobacterial antigens.
Rahman MJ, Chuquimia OD, Petursdottir DH, Periolo N, Singh M, Fernández C.
Infect Immun. 2011 Nov;79(11):4649-56. Epub 2011 Aug 15.PMID: 21844233
Impact of Toll-like receptor 2 deficiency on immune responses to mycobacterial antigens.
Rahman MJ, Chuquimia OD, Petursdottir DH, Periolo N, Singh M, Fernández C.
Infect Immun. 2011 Aug 15. [Epub ahead of print]
PMID: 21844233

Influence of maternal gestational treatment with mycobacterial antigens on postnatal immunity in an experimental murine model.
Rahman MJ, Dégano IR, Singh M, Fernández C.
PLoS One. 2010 Mar 15;5(3):e9699.

Resistance to mycobacterial infection: A pattern of early immune responses leads to a better control of pulmonary infection in C57BL/6 compared with BALB/c mice.
Arko-Mensah J, Rahman MJ, Dégano IR, Chuquimia OD, Fotio AL, Garcia I, Fernández C.Vaccine. 2009 Sep 5.

 


 

Contacts

Cell Biology  Per Ljungdahl, Phone: +46 8 16 41 01

Developmental Biology Christos Samakovlis, Phone: + 46 8 16 15 64

Immunology Marita Troye Blomberg, Phone: + 46 8 16 41 64

Physiology Barbara Cannon, Phone:+ 46 8 16 41 20


 

Imaging Facility, IFSU

Zeiss LSM 780

Vacancies