Aufschnaiter A and Büttner S. Peroxisomal fission controls yeast life span. Cell Cycle. 2015 Jun 23:0


Büttner S, Broeskamp F, Sommer C, Markaki M, Habernig L, Alavian-Ghavanini A, Carmona-Gutierrez D, Eisenberg T, Michael E, Kroemer G, Tavernarakis N, Sigrist S, Madeo F. Spermidine protects against α-synuclein cytotoxicity. Cell Cycle. 2014;13(24):3903-8.


Eisenberg T, Schroeder S, Büttner S, Carmona-Gutierrez D, Pendl T, Andryushkova A, Mariño G, Pietrocola F, Harger A, Zimmermann A, Magnes C, Sinner F, Sedej S, Pieber TR, Dengjel J, Sigrist S, Kroemer G, Madeo F. A histone point mutation that switches on autophagy. Autophagy. 2014 Jun 1;10(6):1143-114


Carmona-Gutierrez D and Büttner S. The many ways to age for a single yeast cell. Yeast. 2014 May 20. doi: 10.1002/yea.3020


Ruckenstuhl C, Netzberger C, Entfellner I, Carmona-Gutierrez D, Kickenweiz T, Stekovic S, Gleixner C, Schmid C, Klug L, Sorgo AG, Eisenberg T, Büttner S, Mariño G, Koziel R, Jansen-Dürr P, Fröhlich KU, Kroemer G, Madeo F. Lifespan extension by methionine restriction requires autophagy-dependent vacuolar acidification. PLoS Genet. 2014 May 1;10(5):e1004347.


Eisenberg T, Schroeder S, Andryushkova A, Pendl T, Küttner V, Bhukel A, Mariño G, Pietrocola F, Harger A, Zimmermann A, Moustafa T, Sprenger A, Jany E, Büttner S, Carmona-Gutierrez D, Ruckenstuhl C, Ring J, Reichelt W, Schimmel K, Leeb T, Moser C, Schatz S, Kamolz LP, Magnes C, Sinner F, Sedej S, Fröhlich KU, Juhasz G, Pieber TR, Dengjel J, Sigrist SJ, Kroemer G, Madeo F. Nucleocytosolic depletion of the energy metabolite acetyl-coenzyme a stimulates autophagy and prolongs lifespan. Cell Metab. 2014 Mar 4;19(3):431-44. doi: 10.1016/j.cmet.2014.02.010.


Büttner S, Habernig L, Broeskamp F, Ruli D, Vögtle FN, Vlachos M, Macchi F, Küttner V, Carmona-Gutierrez D, Eisenberg T, Ring J, Markaki M, Aras Taskin A, Benke S, Ruckenstuhl C, Braun R, Van den Haute C, Bammens T, van der Perren A, Fröhlich KU, Winderickx J, Kroemer G, Baekelandt V, Tavernarakis N, Kovacs GG, Dengjel J, Meisinger C, Sigrist SJ and Madeo F. Endonuclease G mediates α-synuclein cytotoxicity during Parkinson's disease. EMBO J. 2013 Oct 15. doi: 10.1038/emboj.2013.228


Eisenberg T and Büttner S. Lipids and cell death in yeast. FEMS Yeast Res. 2013 Oct 3. doi: 10.1111/1567-1364.12105


Carmona-Gutierrez D, Alavian-Ghavanini A, Habernig L, Bauer MA, Hammer A, Rossmann C, Zimmermann AS, Ruckenstuhl C, Büttner S, Eisenberg T, Sattler W, Malle E, Madeo F. The cell death protease Kex1p is essential for hypochlorite-induced apoptosis in yeast. Cell Cycle. 2013 May 1;12(11).


Büttner S, Faes L, Reichelt NR, Broeskamp F, Habernig L, Benke S, Kourtis N, Ruli D, D’hooge P, Ghillebert R, Eisenberg T, Carmona Gutierrez D, Franssens V, Harger A, Pieber TR, Freudenberger P, Kroemer G, Sigrist SJ, Winderickx J, Callewaert G, Tavernarakis N, Madeo F. The Ca2+/Mn2+ ion-pump PMR1 links elevation of cytosolic Ca2+ levels to α-synuclein toxicity in Parkinson’s disease models. Cell Death Differ. 2012. 10:1038/cdd.2012.142


Rinnerthaler M, Büttner S, Laun P, Heeren G, Felder TK, Klinger H, Weinberger M, Stolze K, Grousl T, Hasek J, Benada O, Frydlova I, Klocker A, Simon-Nobbe B, Jansko B, Breitenbach-Koller H, Eisenberg T, Gourlay CW, Madeo F, Burhans WC, Breitenbach M. Yno1p/Aim14p, a NADPH-oxidase ortholog, controls extramitochondrial reactive oxygen species generation, apoptosis, and actin cable formation in yeast. Proc Natl Acad Sci. 2012. 109 (22):8658–8663.

 

Laun P, Büttner S, Rinnerthaler M, Burhans WC, Breitenbach M. Yeast aging and apoptosis. Subcell Biochem. 2012;57:207-32.


Breitenbach M, Laun P, Dickinson JR, Klocker A, Rinnerthaler M, Dawes IW, Aung-Htut MT, Breitenbach-Koller L, Caballero A, Nyström T, Büttner S, Eisenberg T, Madeo F, Ralser M. The role of mitochondria in the aging processes of yeast. Subcell Biochem. 2012;57:55-78.


Carmona-Gutierrez D, Reisenbichler A, Heimbucher P, Bauer MA, Braun RJ, Ruckenstuhl C, Büttner S, Eisenberg T, Rockenfeller P, Fröhlich KU, Kroemer G, Madeo F. Ceramide triggers metacaspase-independent mitochondrial cell death in yeast. Cell Cycle. 2011;10(22):3973-8.


Swinnen E, Büttner S, Outeiro TF, Galas MC, Madeo F, Winderickx J, Franssens V. Aggresome formation and segregation of inclusions influence toxicity of α-synuclein and synphilin-1 in yeast. Biochem Soc Trans. 2011;39(5):1476-81.


Haemmerle G, Moustafa T, Woelkart G, Büttner S, Schmidt A, van de Weijer T, Hesselink M, Jaeger D, Kienesberger PC, Zierler K, Schreiber R, Eichmann T, Kolb D, Kotzbeck P, Schweiger M, Kumari M, Eder S, Schoiswohl G, Wongsiriroj N, Pollak NM, Radner FP, Preiss-Landl K, Kolbe T, Rülicke T, Pieske B, Trauner M, Lass A, Zimmermann R, Hoefler G, Cinti S, Kershaw EE, Schrauwen P, Madeo F, Mayer B, Zechner R. ATGL-mediated fat catabolism regulates cardiac mitochondrial function via PPAR-α and PGC-1. Nat Med. 2011;17(9):1076-85.


Galluzzi L, Vanden Berghe T, Vanlangenakker N, Buettner S, Eisenberg T, Vandenabeele P, Madeo F, Kroemer G. Programmed necrosis from molecules to health and disease. Int Rev Cell Mol Biol. 2011;289:1-35.


Braun RJ, Sommer C, Carmona-Gutierrez D, Khoury CM, Ring J, Büttner S, Madeo F. Neurotoxic 43-kDa TAR DNA-binding protein (TDP-43) triggers mitochondrion-dependent programmed cell death in yeast. J Biol Chem. 2011 Jun 3;286(22):19958-72.


Büttner S, Ruli D, Vögtle FN, Galluzzi L, Moitzi B, Eisenberg T, Kepp O, Habernig L, Carmona-Gutierrez D, Rockenfeller P, Laun P, Breitenbach M, Khoury C, Fröhlich KU, Rechberger G, Meisinger C, Kroemer G, Madeo F. A yeast BH3-only protein mediates the mitochondrial pathway of apoptosis. EMBO J. 2011 Jun 14;30(14):2779-92.


Carmona-Gutiérrez D, Bauer MA, Ring J, Knauer H, Eisenberg T, Büttner S, Ruckenstuhl C, Reisenbichler A, Magnes C, Rechberger GN, Birner-Gruenberger R, Jungwirth H, Fröhlich KU, Sinner F, Kroemer G, Madeo F. The propeptide of yeast cathepsin D inhibits programmed necrosis. Cell Death Dis. 2011.19;2:e161.


Büttner S, Delay C, Franssens V, Bammens T, Ruli D, Zaunschirm S, de Oliveira RM, Outeiro TF, Madeo F, Buée L, Galas MC, Winderickx J. Synphilin-1 enhances α-synuclein aggregation in yeast and contributes to cellular stress and cell death in a Sir2-dependent manner. PLoS One. 2010 Oct 27;5(10):e13700.


Rockenfeller P, Ring J, Muschett V, Beranek A, Buettner S, Carmona-Gutierrez D, Eisenberg T, Khoury C, Rechberger G, Kohlwein SD, Kroemer G, Madeo F. Fatty acids trigger mitochondrion-dependent necrosis. Cell Cycle. 2010 Jul 15;9(14):2836-42.


Carmona-Gutierrez D, Ruckenstuhl C, Bauer MA, Eisenberg T, Büttner S, Madeo F. Cell death in yeast: growing applications of a dying buddy. Cell Death Differ. 2010 May;17(5):733-4.


Eisenberg T, Carmona-Gutierrez D, Büttner S, Tavernarakis N, Madeo F. Necrosis in yeast. Apoptosis. 2010 Mar;15(3):257-68.


Madeo F, Eisenberg T, Büttner S, Ruckenstuhl C, Kroemer G. Spermidine: a novel autophagy inducer and longevity elixir. Autophagy. 2010 Jan;6(1):160-2.


Carmona-Gutierrez D, Eisenberg T, Büttner S, Meisinger C, Kroemer G, Madeo F. Apoptosis in yeast: triggers, pathways, subroutines. Cell Death Differ. 2010 May;17(5):763-73.


Franssens V, Boelen E, Anandhakumar J, Vanhelmont T, Büttner S, Winderickx J. Yeast unfolds the road map toward alpha-synuclein-induced cell death. Cell Death Differ. 2010;17(5):746-53.


Braun RJ, Büttner S, Ring J, Kroemer G, Madeo F. Nervous yeast: modeling neurotoxic cell death. Trends Biochem Sci. 2010 Mar;35(3):135-44.


Eisenberg T, Knauer H, Schauer A, Büttner S, Ruckenstuhl C, Carmona-Gutierrez D, Ring J, Schroeder S, Magnes C, Antonacci L, Fussi H, Deszcz L, Hartl R, Schraml E, Criollo A, Megalou E, Weiskopf D, Laun P, Heeren G, Breitenbach M, Grubeck-Loebenstein B, Herker E, Fahrenkrog B, Fröhlich KU, Sinner F, Tavernarakis N, Minois N, Kroemer G, Madeo F. Induction of autophagy by spermidine promotes longevity. Nat Cell Biol. 2009 Nov;11(11):1305-14.


Madeo F, Carmona-Gutierrez D, Ring J, Büttner S, Eisenberg T, Kroemer G. Caspase-dependent and caspase-independent cell death pathways in yeast. Biochem Biophys Res Commun. 2009 May 1;382(2):227-31.


Ruckenstuhl C, Büttner S, Carmona-Gutierrez D, Eisenberg T, Kroemer G, Sigrist SJ, Fröhlich KU, Madeo F. The Warburg effect suppresses oxidative stress induced apoptosis in a yeast model for cancer. PLoS One. 2009;4(2):e4592.


Jungwirth H, Ring J, Mayer T, Schauer A, Büttner S, Eisenberg T, Carmona-Gutierrez D, Kuchler K, Madeo F. Loss of peroxisome function triggers necrosis. FEBS Lett. 2008 Aug 20;582(19):2882-6


Low CP, Shui G, Liew LP, Büttner S, Madeo F, Dawes IW, Wenk MR, Yang H. Caspase-dependent and -independent lipotoxic cell-death pathways in fission. J Cell Sci. 2008 Aug 15;121:2671-84.


Büttner S, Bitto A, Ring J, Augsten M, Zabrocki P, Eisenberg T, Jungwirth H, Hutter S, Carmona-Gutierrez D, Kroemer G, Winderickx J, Madeo F. Functional mitochondria are required for alpha-synuclein toxicity in aging yeast. J Biol Chem. 2008 Mar 21;283(12):7554-60.


Almeida B, Büttner S, Ohlmeier S, Silva A, Mesquita A, Sampaio-Marques B, Osório NS, Kollau A, Mayer B, Leão C, Laranjinha J, Rodrigues F, Madeo F, Ludovico P. NO-mediated apoptosis in yeast. J Cell Sci. 2007 Sep 15;120(Pt 18):3279-88.


Büttner S, Carmona-Gutierrez D, Vitale I, Castedo M, Ruli D, Eisenberg T, Kroemer G, Madeo F. Depletion of endonuclease G selectively kills polyploid cells. Cell Cycle. 2007 May 2;6(9):1072-6.


Eisenberg T, Büttner S, Kroemer G, Madeo F. The mitochondrial pathway in yeast apoptosis. Apoptosis. 2007 May;12(5):1011-23. Review.


Büttner S, Carmona-Gutierrez D, Eisenberg T, Ruli D, Madeo F. Conspiracy of yeast killers: the fifth international meeting on yeast apoptosis in Prague, Czech Republic, 3-7 September, 2006. FEMS Yeast Res. 2007 Mar;7(2):351-4.


Büttner S, Eisenberg T, Carmona-Gutierrez D, Ruli D, Knauer H, Ruckenstuhl C, Sigrist C, Wissing S, Kollroser M, Fröhlich KU, Sigrist S, Madeo F. Endonuclease G regulates budding yeast life and death. Mol Cell. 2007 Jan 26;25(2):233-46.


Büttner S, Eisenberg T, Herker E, Carmona-Gutierrez D, Kroemer G, Madeo F. Why yeast cells can undergo apoptosis: death in times of peace, love, and war. J Cell Biol. 2006 ;175(4):521-5.


Braun RJ, Zischka H, Madeo F, Eisenberg T, Wissing S, Büttner S, Engelhardt SM, Büringer D, Ueffing M. Crucial mitochondrial impairment upon CDC48 mutation in apoptotic yeast. J Biol Chem. 2006 Sep 1;281(35):25757-67.


Allen C, Büttner S, Aragon AD, Thomas JA, Meirelles O, Jaetao JE, Benn D, Ruby SW, Veenhuis M, Madeo F, Werner-Washburne M. Isolation of quiescent and nonquiescent cells from yeast stationary-phase cultures. J Cell Biol. 2006 Jul 3;174(1):89-100.


Wissing S, Ludovico P, Herker E, Büttner S, Engelhardt SM, Decker T, Link A, Proksch A, Rodrigues F, Corte-Real M, Fröhlich KU, Manns J, Candé C, Sigrist SJ, Kroemer G, Madeo F. An AIF orthologue regulates apoptosis in yeast. J Cell Biol. 2004 Sep 27;166(7):969-74.


Herker E, Jungwirth H, Lehmann KA, Maldener C, Fröhlich KU, Wissing S, Büttner S, Fehr M, Sigrist S, Madeo F. Chronological aging leads to apoptosis in yeast. J Cell Biol. 2004 Feb 16;164(4):501-7.