Comparative Genomics

Today the genome sequence of thousands of organisms is known, including our own genome sequence and that of many closely related species. The course covers bioinformatical methods to analyse genome, basics of how prokaryote and eukaryote genomes are built, the principles of gene prediction and sequence comparisons.

This course is part of the joint master’s programme in Molecular techniques in life science, together with KTH and KI. The course is not open for application to students outside of the programme.

To understand human biology and origins as well as how life in general has evolved it is necessary to compare these genomes. In this course you will learn how to compare genomes using bioinformatic techniques such as phylogeny and orthology prediction as well as other methods to understand the evolution of genes and genomes.

Moreover, you will learn how to do functional annotation of proteins on the genome scale, and how to analyse the interactome.

After completing the course, the student is expected to:

  • be able to discuss how different genomes are constructed
  • be able to predict genes in a genome sequence
  • be able to discuss and apply methods for sequence comparisons
  • be able to discuss and apply phylogenetic analysis
  • be able to discuss and apply orthology analysis





Examiner

Erik Sonnhammer
Mailerik.sonnhammer@dbb.su.se

The schedule will be available no later than one month before the start of the course. We do not recommend print-outs as changes can occur. At the start of the course, your department will advise where you can find your schedule during the course.
Note that the course literature can be changed up to two months before the start of the course.

Suggested:

Zvelebil, M. J., Baum, J.O. (2007) Understanding Bioinformatics, Garland Science

Course reports are displayed for the three most recent course instances.








Course Coordinator
Erik Sonnhammer, email: erik.sonnhammer@dbb.su.se

Chemistry Section & Student Affairs Office: chemistry@su.se

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