Understanding the complex behaviour of tumor cells is both challenging and critical in the fight against cancer. Techniques, such as in situ sequencing, make it possible to detect RNA within individual cells while preserving their spatial context. Using this approach, my research focuses on the analysis of tumor tissues to reveal the genetic clonality and cellular function of the tumor cells. By combining spatial techniques with computational tools, I aim to better understand how tumors, such as glioblastoma, behave.