Development of new methodology for synthesis of organofluorine compounds

One of three recently registered drug substances contain at least one carbon-fluorine bond. The efforts of the Szabó group are focused on synthesis of new compounds containing C-F, C-CF 3 , C-SCF 3 motifs with a special interest for synthesis of chiral derivatives.

New methodology for fluorine-18 labelling of small organic molecules

Positron Emission Tomography (PET) is currently one of the most advanced medicinal diagnostic methods. PET imaging enables non-invasive monitoring of biochemical/pharmaceutical processes in living organisms. Fluorine-18 labelled compounds are one of the most important tracers in PET diagnostics. The research group is involved in development of new fluorine-18 labelled tracers, which are suitable for diagnostics of cancer and inflammatory disorders.

Asymmetric organocatalysis for synthesis of organoboron reagents

Organoboron compounds are very important building blocks for synthesis of complex bioactive molecules. The Szabó group has developed new methodology for synthesis of chiral organoboron compounds, which are important in asymmetric synthesis. Using boron reagents in selective, catalytic synthesis of new carbon-hetero atom and carbon-carbon bond containing molecules is also a part of the Szabó group's main research interest.