Research group Gunnar von Heijne's research group

Membrane proteins serve a number of very important functions in both prokaryotic and eukaryotic cells. They are built according to structural principles different from those of globular proteins.
Gunnar von Heijne


Membrane protein assembly and structure

A full understanding of membrane proteins requires a conceptual framework where processes of protein translocation across membranes and the physical chemistry of lipid-protein interactions play major roles.

Work in our lab has pointed to the central importance of positively charged amino acids as determinants of membrane protein topology, has led to the development of new theoretical methods for predicting transmembrane segments, and has illuminated many aspects of membrane protein assembly in both prokaryotic and eukaryotic cells. Ongoing work is directed towards a better understanding of the folding and assembly of membrane proteins.

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Department of Biochemistry and Biophysics

Swedish Research Council Awards Seven Grants to DBB Researchers

The Swedish Research Council (Vetenskapsrådet) has awarded research grants to seven researchers at the Department of Biochemistry and Biophysics (DBB). Vetenskapsrådet funds awards for both newly established researchers, and for established researchers to undertake studies in a wide range of areas.

Close-up images of protein folding

Proteins are the building blocks of life. They build our cells, send signals and transport substances. But they will only work correctly if they attain their exact 3-dimensional form. Gunnar von Heijne is demonstrating at a previously inconceivable level of detail how protein folding is achieved.

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