Research group Erik Sonnhammer's research group
We are only starting to understand the functional networks of the proteins encoded in the now sequenced human genome. The group is addressing this issue using computational approaches, such as hidden Markov models, evolutionary models, and discriminant statistical methods - aiming to predict function, both with regards to biochemical activity and pathways.
To predict pathway interactions we are developing integrative computational methods and databases with a focus on identifying new disease genes. The resulting networks are available at http://FunCoup.sbc.su.se/
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