Stockholm university

Research group Marta Carroni's research group

In our group, we use mainly cryo-EM to discover molecular regulatory mechanisms. We combine the technique also with cryogenic electron tomography (cryo-ET) and work at developing combinatory methods with fluorescence microscopy. We follow two main lines of research.

In the first one, we aim at understing the molecular mechanics of AAA+ proteins involved in cellular protein quality control. AAA+ are fascinating systems as they  can perform extremely different tasks in the cell while sharing the same basic structural fold. We look into the special structural inserts and interaction with adaptor proteins that confer AAA+ chaperones resistance to stress in both bacteria and humans. 

In a second line of research we use cryo-EM as a tool for longitudinal epitope mapping of antibody response in animal models and humans with the aim of gaining insights useful for better vaccine design or for understanding autoimmune diseases. 

The group works in close proximity to the cryo-EM national unit at SciLifeLab, which I also supervise.

Group members

Group managers

Marta Carroni

Docent

Department of Biochemistry and Biophysics
Marta Carroni

Members

Maximilian Kahle

Postdoc

Department of Biochemistry and Biophysics

Tim Schulte

Bioinformatician

Department of Biochemistry and Biophysics
Tim Schulte

Piotr Draczkowski

Bioinformatician

Department of Biochemistry and Biophysics
Piotr Draczkowski

Koen Jurgens

PhD student

Department of Biochemistry and Biophysics
Koen Jurgens

Stavros Azinas

Researcher

Department of Biochemistry and Biophysics
Stavros Azinas

Mathieu Coincon

Researcher

Department of Biochemistry and Biophysics
Mathieu Coincon

Julian Conrad

Research engineer

Department of Biochemistry and Biophysics
Julian Conrad

Lisa Dana R Engelhardt

PhD student

Department of Biochemistry and Biophysics
Lisa Engelhardt

Dustin Morado

Research engineer

Department of Biochemistry and Biophysics

Karin Walldén

Lab Manager

Department of Biochemistry and Biophysics
Karin Walldén

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