The course covers the biochemistry of the nervous system; neurotransmitter synthesis and metabolic mechanisms at the synapse, release and re-uptake/degradation of classical neurotransmitters and peptide transmitters. Receptors for neurotransmitters and their ligands are described from a chemical-pharmacological point of view and the relevance of these molecules and their interactions for development of tolerance, supersensitivity and long term potentiation are discussed. Aspects of neurochemistry as a basis for neuropharmacology are discussed.
The course is useful for advanced studies in biology or chemistry or for work in the pharmaceutical industry.
The course consists of lectures, laboratory exercises and an independent literature seminar.
The course literature consists of lecture hand-outs and scientific articles handed out in connection with lectures.
For those who want to read more we can recommend the book; Basic Neurochemistry: Principles of molecular, cellular and medical neurobiology. Editors ST Brady, GJ Siegel, RW Albers & DL Price. Eighth edition, 2012, Academic Press, ISBN: 978-0-12-374947-5
For additional information: Anna-Lena Ström, course organizer