Research projects

Bacterial interaction with human neutrophils

 Bacterial adhesion to human is mediated via the pili in several bacteria. Upon bacterial adhesion to epithelial cells, the target cell releases cytokines (such as Interleukin 8 and C5a), which recruits neutrophil granulocytes, most often called polymorphonuclear cells (PMNs) to the site of infection.

Cell cycle regulation during bacterial infection

It is becoming increasingly apparent that the human cell cycle is affected by bacterial infections. Many bacterial pathogens manipulate the host cell cycle to benefit bacterial attachment, survival and growth within the host.

Lactobacilli decelerates cell cycle progression

Lactobacilli act as a first line of defense against infections by preventing colonization of pathogenic bacteria. A disruption of the population balance or depletion of lactobacilli increases the incidence of bacterial infections.

Helena Aro

Helena Aro, Associated Professor

Visiting address:
Svante Arrhenius väg 20C
Room E456

Postal address:
Stockholm University
Department of Molecular Biosciences,
The Wenner-Gren Institute
SE-106 91 Stockholm

Telephone: +46 8 16 4189
Fax: +46 8 16 4209

Group members

Linda Weyler
Manuel Forsberg