Research projects


Tube maturation: From morphogenesis to function

The development of air-filled respiratory organs is crucial for survival. We have combined live imaging with genetics to dissect airway maturation. Initially, a secretion burst deposits proteins into the nascent tracheal tubes. Solid material is then rapidly cleared and shortly thereafter liquid is removed from the lumen.


Grainy head in tube size control and wound healing

Grainy head (grh), is a phylogenetically conserved transcription factor. In grh mutants, the apical epithelial cell membrane is overgrown resulting in overgrown airway tubes.

Christos Samakovlis


Christos Samakovlis, Professor

Visiting address:
Svante Arrhenius väg 20C
Room E353

Postal address:
Stockholm University
Department of Molecular Biosciences,
The Wenner-Gren Institute
SE-106 91 Stockholm

Telephone: +46 8 16 1564
Fax: +46 8 16 4209

Group members

Alexandra Firsova
Chie Hosono
Andreas Liontos
Dan Liu
Ryo Matsuda
Hong-Phuong Nguyen
Ana Pinheiro
Alexandros Sountoulidis
Vasilios Tsarouhas
Georgia Tsikala