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Alyssa Woronik

Alyssa Woronik

Doktorand

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Arbetar vid Zoologiska institutionen
Telefon 08-16 40 52
E-post alyssa.woronik@zoologi.su.se
Besöksadress Svante Arrheniusväg 18b
Rum D 548
Postadress Zoologiska institutionen: Populationsgenetik 106 91 Stockholm

Publikationer

I urval från Stockholms universitets publikationsdatabas
  • 2017. Alyssa Woronik, Christopher W. Wheat. Journal of Evolutionary Biology 30 (1), 26-39

    Although alternative life-history strategies exist within many populations, very little is known about their genetic basis and mechanistic insight into these traits could greatly advance the understanding of eco-evolutionary dynamics. Many species of butterfly within the genus Colias exhibit a sex-limited wing colour polymorphism, called Alba, which is correlated with an alternative life-history strategy. Here, we have taken the first steps in localizing the region carrying Alba in Colias croceus, a species with no genomic resources, by generating whole genome sequence of a single Alba mother and two sequencing pools, one for her Alba and another for her orange, offspring. These data were used in a bulk-segregant analysis wherein SNPs fulfilling the Mendelian inheritance expectations of Alba were identified. Then, using the conserved synteny in Lepidoptera, the Alba locus was assigned to chromosome 15 in Bombyx mori. We then identified candidate regions within the chromosome by investigating the distribution of Alba SNPs along the chromosome and the difference in nucleotide diversity in exons between the two pools. A region spanning similar to 5.7 Mbp at the 50 end of the chromosome was identified as likely to contain the Alba locus. These insights set the stage for more detailed genomic scans and mapping of the Alba phenotype, and demonstrate an efficient use of genomic resources in a novel species.

Visa alla publikationer av Alyssa Woronik vid Stockholms universitet

Senast uppdaterad: 18 september 2018

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