Research projects

B-cell activation and memory

Immunological memory and the germinal centre reaction

The immune system requires the cognate interactions of T cells, B cells, and antigen presenting cells to respond to invading antigens/pathogens. The peripheral organs where the immune response occurs are organized into microanatomic compartments that are composed of T cell zones and B cell follicles. B cell responses to thymus dependent (TD) antigens begin in the T cell zones of secondary lymphoid tissues where T and B cells initiate antigen and costimulus dependent proliferation.

Tuberculosis

The innate immune system in Mycobacterium infection

The innate immune system provides an early response against invading microorganisms while the adaptive immune system operates at later stages when the pathogen has infected the host. In the first hours of exposure to and invasion by the pathogen, two outcomes can be schematically described: rejection/destruction of the pathogen (by innate immunity) and infection of the host (despite innate immunity).

Carmen Fernández

 

Carmen Fernández, Professor

Visiting address:
Svante Arrhenius väg 20C
Room F522

Postal address:
Stockholm University
Department of Molecular Biosciences,
The Wenner-Gren Institute
SE-106 91 Stockholm

Telephone: +46 8 164 164
Fax: +46 8 16 4209
E-mail: carmen.fernandez@su.se