Stockholm university

Life Science

On this page we collect articles about research in Life Science at Stockholm University and SciLifeLab.

Foto: Hyunho Kim

News

Department of Molecular Biosciences, The Wenner-Gren Institute

Exploring Immune Response Staphylococcal Enterotoxin A - Interview with Clàudia Arasa Cuartiella

On Friday, April 4, 2025, Clàudia Arasa Cuartiella will defend her doctoral thesis, “Unraveling the immune response to Staphylococcal Enterotoxin A – From calm seas to cytokine storms: navigating the superantigenic tide”, at Stockholm University. Her research delves into how Staphylococcal Enterotoxin A (SEA), a virulence factor of Staphylococcus aureus, interacts with the immune system. Before the defence, we have had the opportunity to have a short interview.

Life Science - Theme page DNA Research - Theme page
Department of Biochemistry and Biophysics

Birds and mammals build advanced brain circuits using different developmental mechanisms

The area in the brain responsible for complex cognitive functions have different origin in different species such as mammals, birds, and reptiles new research show. These findings indicate that these structures and circuits are not homologous, but rather the result of convergent evolution.

Brain Research - Theme page Chemistry - Theme page DNA Research - Theme page Plants, Animals and Nature - Theme page SciLifeLab - Theme page Life Science - Theme page
Forskaren Qiaolin Deng

10 MSEK to Strengthen Collaboration Between Research and Societal Impact

Qiaolin Deng has been awarded 3 MSEK in project funding from Region Stockholm for her research project on how the placenta is affected by type 1 diabetes during pregnancy. In total, nine researchers from Stockholm University (SU) have been granted 10 MSEK in project funding.

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SUBIC - Stockholm University Brain Imaging Centre

Four projects awarded SUBIC time grants

Four projects have received time grants from the Stockholm University Brain Imaging Center (SUBIC). SUBIC congratulates the researchers and encourages other Stockholm University researchers to apply for the next grant in 2025.

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Department of Ecology, Environment and Plant Sciences

Postdoc Fellowship in Marine Microbiology

A postdoctoral stipend is available with an emphasis on planktonic N2 fixing symbioses. The position is sponsored by the Carl Trygger Foundation to the laboratory of Professor Rachel A Foster at Stockholm University in the Department of Ecology, Environment and Plant Sciences. At the Department of Ecology, Environment and Plant Sciences, research and teaching are conducted in an international environment. The department has approximately 100 employees, including 25 research groups, 10 postdocs and approximately 35 are PhD students.

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Tanja Slotte receives funding from the Knut and Alice Wallenberg Foundation

Each year, the Knut and Alice Wallenberg Foundation awards research grants in the fields of medicine, science, and technology to research projects that are judged to have such high scientific potential that they are likely to lead to future scientific breakthroughs. Each project is evaluated by a group of international experts in the respective field.

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Department of Molecular Biosciences, The Wenner-Gren Institute

Study shows that preterm infants may be more vulnarable to microbal exposure

In a new study, Group Sverremark-Ekström shows that extremely preterm infants have monocyte characteristics and functional features that deviate from infants born full-term. Some of these differences persist until they reach an age corresponding to full-term, potentially making them more vulnerable to microbial exposures during the first months of life.

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Portraits of six researchers combined

Six researchers share SEK 175 million from the Wallenberg Foundation

The importance of Arctic methane emissions for the climate, how matter is formed and broken down, evolutionary shifts in the plant kingdom, and new effective methods for producing bioactive substances that will meet future needs for medicines and advanced electronics. These are just a few examples of basic research at Stockholm University that has received funding from the Knut and Alice Wallenberg Foundation.

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Department of Molecular Biosciences, The Wenner-Gren Institute

Mapping the sex life of Malaria parasites reveals the genetics underlying Malaria transmission

Malaria is caused by a eukaryotic microbe of the Plasmodium genus, and is responsible for more deaths than all other parasitic diseases combined. In order to transmit from the human host to the mosquito vector, the parasite has to differentiate to its sexual stage, referred to as the gametocyte stage. Unlike primary sex determination in mammals, which occurs at the chromosome level, it is not known what causes this unicellular parasite to form males and females. New research at Stockholm University has implemented high-resolution genomic tools to map the global repertoire of genes of gametocyte development towards the male or the female sexual fates.

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Schematiskt diagram för hur parasitens sexuella utvecklingen går till i människan.
Institutionen för molekylär biovetenskap, Wenner-Grens institut

Kartläggning av malariaparasiters sexliv avslöjar genetiken bakom spridningen av malaria

Malaria som orsakas av en mikrob av släktet Plasmodium leder till fler dödsfall än alla andra parasitsjukdomar tillsammans. För att kunna överföras från människan till myggan måste parasiten gå igenom ett stadium där den bildar hanar och honor. Inuti myggan förenas de som en spermie och ett ägg och skapar en så kallad zygot som genomgår sexuell korsning. En forskargrupp vid Stockholms universitet har, med hjälp av avancerad teknologi, lyckats kartlägga de gener som gör det möjligt för parasiten att gå från det helt asexuella utvecklingsstadiet i blodet till ett sexuellt stadie där den bildar hanar och honor, vilka sedermera tas upp av myggan.

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Illustration of how malaria parasites are transmitted.
Department of Molecular Biosciences, The Wenner-Gren Institute

First spatial map of malaria infection in the liver opens up for more effective malaria treatments

For the malaria parasite to reach the blood of its human host, it must first enter the liver, where only a small number of parasites differentiate and replicate for upwards of seven days, making it a bottleneck in the parasite’s lifecycle. This bottleneck makes the liver stage an optimal target for effective and long-lasting vaccines against the disease. Using Spatial Transcriptomics and single-cell RNA-sequencing technologies, researchers at Stockholm University have for the first time managed to create a spatio-temporal map of malaria infection in the mouse liver. A study that was recently published in Nature Communications.

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Department of Environmental Science

New study reveals transgenerational effects of pesticide linuron on frogs

Grand-offspring of male frogs exposed to the pesticide linuron exhibited changes in their DNA that was linked to significant physiological impacts, a study from Stockholm University reveals. The research highlights the profound transgenerational consequences of environmental pollution on amphibian populations, which are already under threat of extinction. The study is published in the journal Science of the Total Environment.

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Iskra följer forskare som jobbar med mikroskop
Department of Biochemistry and Biophysics

Mapping the brain's serotonin pathways increases knowledge of our emotions

Fear and curiosity are emotions that determine how adventurous or cautious we are. But how are our emotions controlled by biological factors in the brain's nerve cells? New research shows that clearly defined serotonin pathways in the brain and their connections to for example amygdala and hypothalamus affect how we feel and act.

DNA Research - Theme page Brain Research - Theme page Health and Living Conditions - Theme page Chemistry - Theme page Life Science - Theme page SciLifeLab - Theme page Psychology and Human Behaviour - Theme page
Noushin Emami tittar in i värmeskåp för myggor

Malaria scientist decodes the world's deadliest parasites

The malaria mosquito is spreading some of the world's deadliest diseases, but not on its own. It is controlled by ancient parasites that use their code language to make their host, human or animal, act in a way that benefits its survival. A code language that molecular biologist Noushin Emami at Stockholm University is working to decode.

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Department of Environmental Science

Scientists to unveil how chemical exposure can affect generations to come

Research led by Oskar Karlsson, Assistant Professor at the Department of Environmental Science, aims to shed light on the long-term effects of chemical exposure across generations. Karlsson's team is tackling the daunting task of safeguarding human health against an estimated 350,000 chemicals in the market, a figure likely on the lower side.

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Department of Environmental Science

Upholding Integrity at the UN's Science-Policy Panel on Chemicals and Waste

In anticipation of the UN's critical working meeting in Nairobi from December 11-15 to establish a science-policy panel for the responsible management of chemicals and waste and to prevent pollution, researchers are raising concerns about the potential involvement of the chemical industry in the panel.

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Department of Environmental Science

Anneli Kruve Awarded ERC Consolidator Grant for Innovative Project 'LearningStructurE'

Associate Professor Anneli Kruve has been awarded funding from the European Research Council (ERC) for her pioneering project, "Machine Learning and Mass Spectrometry for Structural Elucidation of Novel Toxic Chemicals" - or simply 'LearningStructurE.'

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Sarah Steimer
Department of Environmental Science

Strong impact on air quality by the Kagghamra fire revealed in new study

A recent study conducted by researchers from the Department of Environmental Science at Stockholm University has shed new light on the impact of the Kagghamra fire, which occurred south of Stockholm in December 2020, on the air quality of nearby residential areas.

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Mars perseverance debris
Department of Environmental Science

Crafting “a New Song” for Mars and Beyond

As governments and private entities prepare to send humans to Mars, the mission brings significant environmental challenges. While the logistics of sustaining life on the Red Planet have been studied extensively, there's a notable gap regarding the impact of chemicals and materials used during human exploration.

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Department of Biochemistry and Biophysics

Radical Tool in Nature's Chemistry Toolbox Depicted

Researchers at DBB have determined the structure of one of nature's sharpest chemical tools, a protein radical. The results help us understand how nature can carry out very challenging chemical reactions and can ultimately be used in both medicine and green chemistry applications.

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Researchers develop first method to study microRNA activity in single cells

Researchers at Stockholm University and SciLifeLab have developed the first method to uncover the tasks that microRNAs perform in single cells. This is a huge improvement over existing state-of-the-art methods that require millions of cells and will for the first time allow researchers to study microRNAs in complex tissues such as brains. The study was published in the journal Nature Biotechnology.

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Aspirin protects against genotoxicity by promoting genome repair

Acetylsalicylic acid (aspirin) is arguably the oldest drug in the history of medicine. In a study published in Cell Research, researchers at Stockholm University and the University Medical Center Freiburg, have identified a new mechanism of aspirin. They show that aspirin promotes genome repair and can protect mice and cells against the toxic effects of irradiation and mutagenic chemicals. This new mechanism may help explain many of the health benefits of aspirin including cancer prevention.

DNA Research - Theme page Health and Living Conditions - Theme page Life Science - Theme page
Mätning av strålning.

Great uncertainty over risk assessment for low-dose radiation

Have we overestimated the health risk posed by low doses of ionising radiation, such as those in houses with radon? And, have we underestimated the risk of exposure to combined types of radiation? Andrzej Wojcik, from Stockholm University, is using specially constructed equipment to investigate the potential effects that low doses of radiation may have on our bodies.

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Department of Materials and Environmental Chemistry

"PRISMAS has a unique collaborative and multicomponent environment and connects fundamental science

A new intersectoral and interdisciplinary project between nine Swedish Universities and MAX IV – a Ph.D. programme called PRISMAS – launches in January 2023. The program is dedicated to the UN Sustainable Development Goals and Horizon Europe's essential research and innovation areas. The project will create a connected network of next-generation X-ray experts, enabling various stakeholders to take full advantage of world-leading synchrotron facilities such as MAX IV, while tackling current societal challenges in the same breath.

Chemistry - Theme page Sustainable Chemistry - Theme page Life Science - Theme page
Department of Biochemistry and Biophysics

New method for mapping cancer paves the way for treatment of incurable brain cancer in children

Children diagnosed with brain cancer often die within a year of their initial diagnosis because there are no effective treatments for this rare form of cancer. But by visualizing the cancer cells, researchers have now gained a better understanding of what the tumors look like. The hope is that it will lead to new treatment methods. This is shown by a study with researchers at, among others, Stockholm University and SciLifeLab, recently published in Nature Genetics.

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Department of Materials and Environmental Chemistry

Anneli Kruve receives VR funding to study Endocrine Disruptives using AI in silico !

Congratulations to MMK’s Anneli Kruve who received a VR grant from the Medicine and health area! The project “MS2Tox: Deep Learning for Automated Prediction of the Endocrine Disruptive Potency of Chemicals in Complex Mixtures” will evaluate the possibility of combining non-target liquid chromatography high resolution mass spectrometry (LC/HRMS) and AI to better predict the hazard of the chemicals.

Chemistry - Theme page Life Science - Theme page Sustainable Chemistry - Theme page
Department of Molecular Biosciences, The Wenner-Gren Institute

Discovery of a neural circuit for sweet and bitter taste

Yunpo Zhao, Jianli Duan and Ylva Engström, together with collaborators in the US, have discovered that a cluster of neurons control sugar and bitter sensitivity in the fruit fly Drosophila. These neurons originate from the same neural stem cell and use the inhibitory neurotransmitter GABA to control taste sensation.

Life Science - Theme page
Department of Molecular Biosciences, The Wenner-Gren Institute

Identity theft the secret of the cat parasite's success

The parasite Toxoplasma is carried by a large portion of the global human population. Now a study led by researchers at Stockholm University shows how this microscopic parasite so successfully spreads in the body, for example to the brain. The parasite infects immune cells and hijacks their identity. The study is published in the scientific journal Cell Host & Microbe.

Life Science - Theme page
How commensal bacteria prime antiviral immunity

The gut microbiota protects against viral infections by keeping the immune system alert

The microbiota is fundamental for health. But how these non-invasive microbes communicate with the rest of the body to influence host physiology is not fully understood. Researchers from Stockholm, Umeå, and Gothenburg Universities, Sweden report how the gut microbiota is essential for natural resistance to viral infections. They show that the release of the membrane vesicles from the gut microbiota leads to the systemic delivery of bacterial DNA to host cells. This triggers the cytosolic cGAS-STING-IFN-I axis for innate immune DNA sensing, thereby protecting distal organs against viral infections. The study is published in the journal Immunity.

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Department of Biochemistry and Biophysics

The world's most dangerous poison can be of great benefit as a drug

Pål Stenmark sees botulinum toxin – the world's most dangerous poison – as a lego building kit he can change so that it gets new features. One goal is to develop new and more effective drugs, including for pain. Through molecular genealogy, he has also found a new family of botulinum toxins, where a variant can fight malaria mosquitoes.

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Department of Biochemistry and Biophysics

Scientists show how a salt transporter linked to hypertension and diabetes works

NHA2 is a protein spanning the membrane in kidney and -cells that absorbs salt and its activity is linked with hypertension and diabetes in humans. The transporter-protein exchangers the movement of sodium ions across cell membranes with the movement of protons. Researchers at Stockholm University have now determined what the protein looks like and how the protein adapts to the membrane. These findings shed new light into this important biological mechanism, and provide a basis for structural-based drug discovery.

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Department of Biochemistry and Biophysics

Basic research for the benefit of ALS patients

By understanding why certain nerve cells and the muscles they control are resistant to fading in the deadly disease ALS, it is possible to create new possibilities for treatments. Researchers at Stockholm University are now trying to identify and transfer the properties of these resistant nerve cells.

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Pål Stenmark

The world’s most dangerous poison may be a valuable pharmaceutical

Pål Stenmark regards botulinum toxin – the world’s most dangerous poison – as a set of building blocks he can redesign and give new functions. One aim is to produce new and more effective pharmaceuticals, including pain treatments. Using molecular research, he has also found a new family of botulinum toxins, where one variant can help counteract malaria mosquitoes.

Chemistry - Theme page Health and Living Conditions - Theme page Life Science - Theme page
Photo: Hyunho Kim

Mapping energy conversion in cells

Billions of years of evolution are behind the ingenious protein machinery in nature’s cells, which captures and converts energy. Professor Ville Kaila is conducting a detailed study of the structure and function of the proteins to learn more about the energy conversion process. That knowledge may eventually result in therapies for diseases where the powerhouses of the cells fall short.

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African clawed frog

Multigenerational effects of pesticides

The effects of the endocrine disruptor linuron on frogs are not limited to those exposed, but are passed on to their offspring and grand-offspring. First generation offspring have reduced body weight and decreased fertility, while second generation offspring have increased body weight and a disrupted metabolism. This is demonstrated by a new study conducted by researchers at Uppsala University and Stockholm University that has now been published in the journal Science of the Total Environment.

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Videos

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Research projects

Argonaute TRIBE

Antibody-based methods such as CLIP can detect direct interactions between microRNAs and their mRNA targets in cell populations with nucleotide resolution. However, these methods typically require millions of cells, and cannot be applied to study the single cells where the interactions occur.

Cell Biology of nutrient regulated gene expression

Proteins with multiple membrane-segments (MS) initially insert into the endoplasmic reticulum (ER) of eukaryotic cells. Little is known how such proteins attain native functional structures. We study the ER membrane chaperone Shr3 that specifically facilitates the folding of all 18 members of the yeast amino acid permease family of proteins with 12 MS.

Research
Cell Motility and the role of Profilin

This project reflects a long-standing interest in eukaryotic cell motility, i.e. movements of intracellular structures and migration of whole cells. Profilin is a coordinator of the two principal force generating machineries behind virtually all cell motility as first revealed by us and therefore takes a special interest in our studies.

Research
Cell-type specific role of chromatin organization

Eukaryotic genomes are folded into high-order chromatin domains, which intrinsically affects all DNA-dependent processes. We study how chromatin architectural proteins regulate gene expression during dynamic developmental processes.

Community dynamics of systemic diseases on the wood anemone

I am fascinated by the spatial and eco-evolutionary dynamics of host-parasite interactions. We do lack some generality though: many of the existing studies have (for good reasons!) focused on single pathogen species, and on non-systemic diseases with high extinction-colonization rates.

DataLEASH: LEarning And SHaring under Privacy Constraints

With massive amounts of personal data being generated, privacy has become a great challenge. This project studies how machine learning can be used for sharing language models without risking to share information that may identify individuals.

Genre photo: Multi-colored text on a computer screen. Photo: Shahadat Rahman/Unsplash.
Ecosystem mapping in the Central Arctic Ocean

The marine ecosystem around the North Pole, the Central Arctic Ocean (CAO), is in fast transition from a permanently to a seasonally ice-covered ocean as a result of global warming. The sea-ice loss will enable summer access to the CAO for non-icebreaking ships, including fishery vessels, in the near future and this project is assessing the impact.

Establishment of epigenetic landscapes

Epigenetic patterns of histone modifications contribute to the maintenance of tissue-specific gene expression, but little is known about how such patterns are initially formed during early embryo development. We study this process in Drosophila.

Federated Health: A Nordic Federated Health Data Network

Electronic health records are full of important information about diagnoses and treatments of patients. Sharing this information in a federated health data network, across hospitals in the Nordic countries, will improve the quality of health care.

Genre photo: Lots of medicine in different colors in a person’s hand.
Health Bank de-identification tool and its practical use

The aim of this project is to enable the practical use of methods for de-identification of clinical free text written in Swedish. The HB Deid tool will be tested on textual patient data from Region Stockholm and not only in a laboratory environment at Stockholm University.

Genre photo: Stethoscope, pen and paper. Photo: Teerawut Masawat/Mostphotos.
Metabolic regulation and spatio-temporal aspects of fungal virulence in situ

Amino acids are essential nutrients that serve as building blocks of proteins and some are efficiently metabolized for energy. Eukaryotic cells respond to extracellular amino acids by enhancing their uptake. We study the molecular mechanisms underlying this response and the role of amino acid metabolism in promoting virulent growth of human fungal pathogens.

OrganoFeed

The OrganoFeed project intends to make lab-grown mini-organs – organoids – more reliable for research. Using AI and microfluidics, it fine-tunes the organoid environment in real time, reducing errors. This could improve drug testing and even help replace animal experiments.

Test tubes being filled with pink liquid.
Paleotranscriptomics

Today, sequencing of DNA from ancient samples is a standard method in Paleogenomics, however, RNA is generally unstable due to the ubiquitous presence of RNases in the environment.

Research
Patient and Public AI-assisted Interventions

With better descriptions of a patient’s state and history, more efficient recommendations can be provided. We explore how AI tools can be put to practical use in healthcare. We focus on complex and multimodal data and use cases such as COVID-19 public health interventions or patient phenotyping for adverse drug events, sepsis, or cancer.

Illustration showing a medical doctor, test tubes and a robot involved in heart surgery.
SeaLab

SeaLab is a joint research venture between the Baltic Sea Centre at Stockholm University and the Environmental Genomics group at SciLifeLab. By combining biogeochemical, ecological, molecular and meta-omic expertise and know-how, the aim is to understand the fundamental microbial processes of coastal ecosystems.

Undervattensbild med blåstång där ytan och land skymtar.
The Insect Biome Atlas

A large-scale insect collection project taking place in Sweden and Madagascar. The main aim of the project is to describe in detail the insect faunas of these two biologically and geologically very different countries.

The importance of the MEP pathway in the microbiome and its effect on behavior

Our main aim is to study the effects of bacterial phosphoantigens (HMBPP and IPP) on appetite. We introduced these into mice by gavage and followed the differences in weight gain and gene transcription from relevant tissues. An unexpected effect on male salivary glands focused our interest also on their effects on immune response.

Research
The physiology of thermogenesis

Nonshivering thermogenesis emanates from the activity of the mitochondrial protein UC P1 in brown adipose tissue. We use novel model systems to advance the understanding of mammalian thermogenesis.

Research
Transcription, coregulators and histone acetylation

Gene transcription is essential for cell identity and its misregulation causes disease. This project explores the connection between transcription and chromatin modifications that make genes accessible to the transcriptional machinery.

Research
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Research groups

Group Andréasson

We study how cells safeguard health and aging by maintaining their proteomes functional. Our research develops fundamental insight into the mechanisms of the proteostasis system.

Claes Andréasson
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Group Ankarklev

Our team studies the biology underlying malaria transmission, with the ultimate goal of enabling novel strategies to hamper the spread of the disease

Johan Ankarklev
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Group Barragan

Our current research on the pathobiology of parasitic infections integrates molecular parasitology with immunology and cell biology to understand how obligate intracellular parasites interact with the host.

Antonio Barragan
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Group Bengtsson

Obesity is a major inducer of type II diabetes and it is estimated by the World Health Organization that over 500 million people worldwide suffer from either of these disorders, with the incidence increasing dramatically over the last 10 years.

Tore Bengtsson
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Group Bryant

We aim to create a universal molecular framework, where any molecule can be predicted with AI. With this technology, the design of new molecules will be possible at the click of a button – for any application.

Fotograf: Patrick Bryant
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Group Büttner

We study how different organelles within a cell communicate and how this interorganellar connectivity contributes to protein homeostasis and cellular fitness during aging.

Sabrina Büttner
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Group Dai

Regulation of cell fate decision is fundamental to development, disease, and regeneration. We address how gene regulatory systems guide the assembly of complex biological patterns by investigating stem cell biology and cell fate decision mechanisms.

Qi Dai
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Group Deng

We explore the intricate relationship between genetics and environmental factors in shaping offspring health. By studying germline development, placental function, and the impact of early-life exposures, we aim to uncover how parental health influences disease risk across generations.

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Group Emami

We work on infectious-disease biology with a focus on host-pathogen-vector signalling-communication. We provide a fundamental/quantitative description of communication in infection-biology/behaviour plasticity, and genetics towards the design of novel scientific technologies.

Noushin Emami
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Group Engström

We study gene expression with a focus on the role of POU/Oct transcription factors in development, stem cell regulation, cancer and immunity. We use the fruitfly Drosophila as a model organism and utilize the genetic tools developed for this organism, in combination with high-throughput expression analyses, high resolution microscopy and live-cell imaging.

Ylva Engström
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Group Faye

Our aim is to study the effects of bacterial phosphoantigens (HMBPP and IPP) on appetite. We introduced these into mice by gavage and followed the differences in weight gain and gene transcription from relevant tissues. An unexpected effect on male salivary glands focused our interest also on their effects on immune response.

Ingrid Faye
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Group Gekara

The immune system that kills disease-causing microbes and heals tissues, and the DNA repair system that maintains gene expression are essential for life. However, they require careful regulation to prevent the destruction of own tissues. The goal of my research is to better understand these systems and find new strategies in the treatment of diseases.

Nelson Gekara
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Group Jastroch

We investigate the physiology and molecular mechanisms of energy metabolism from the organism to the molecule. We focus on metabolic aspects during obesity, adipose tissue biology, mitochondrial mechanisms and thermogenesis.

Martin Jastroch
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Group Jonas

Our group studies how bacteria grow and reproduce in fluctuating environments. We use a combination of genetics, cell biology and biochemistry to dissect the molecular mechanisms underlying bacterial growth and cell cycle progression and how these processes are regulated under changing environmental conditions to ensure bacterial survival.

Kristina Jonas
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Group Keipert

The main focus of our research group is to understand how endocrine crosstalk, involving adipose tissue, controls mammalian energy metabolism. Our goal is to identify target mechanisms for novel therapeutic strategies to fight obesity.

Susanne Keipert
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Group Ljungdahl

Amino acids are essential nutrients that serve as building blocks of proteins and some are efficiently metabolized for energy. Eukaryotic cells respond to extracellular amino acids by enhancing their uptake. We study the molecular mechanisms underlying this response and the role of amino acid metabolism in promoting virulent growth of human fungal pathogens.

Per Ljungdahl
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Group Nedergaard & Cannon

Nonshivering thermogenesis emanates from the activity of the mitochondrial protein UC P1 in brown adipose tissue. We use novel model systems to advance the understanding of mammalian thermogenesis.

No photo
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Group Ozata

As a new research group aiming to construct an international work environment with a mutual respect, our main objective is to enthusiastically investigate how a mammalian male germ cell commits to become a functional sperm. Our studies will therefore advance our understanding of sperm development and may suggest approaches to promote fertility.

Deniz Ozata
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Group Riedel

Aging is a strong determinant of human health and longevity. We study the molecular mechanisms that regulate aging, aiming to eventually target them for therapeutic purposes.

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Group Samakovlis

Branched tubular organs are found in most animals. They include tissues like the lung, kidney and the vascular system. Many of the basic principles of tube construction in these organs are conserved among species. We aim to describe the genetic programs leading to the formation of a functional epithelial tubular network.

Christos Samakovlis
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Group Spetz

We are exploring basic mechanisms regarding a group of small non-coding oligonucleotides and their therapeutic potential. We have discovered that a set of single-stranded oligonucleotides temporarily inhibit certain endocytic pathways and thereby modulate innate immune responses as well as providing anti-viral effects.

Anna-Lena Spetz
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Group Theopold

We regret to inform that our beloved colleague Ulrich Theopold passed away in end of September 2023. All our thoughts go out to his family. 

Ulrich Theopold
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Group Visa

Our research aims at understanding the mechanisms by which RNA and RNA degradation by the exosome contribute to chromatin regulation, gene expression and genome integrity.

Neus Visa
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Group Wojcik

We are interested in biological and physical factors affecting cellular and molecular effects of ionising radiation. Focus is on DNA damage and repair, chromatin structure, low doses, low dose rates, mixed radiation qualities, fractionation and modulation by chemical and physical factors.

Andrzej Wojcik
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Group Åström

We explore how cells maintain genome stability using yeast cells as a model. Specifically, we investigate repetitive DNA such as telomeres and the rDNA loci. We are interested in both telomere maintenance and DNA repair mechanisms.

Stefan Åström
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Polar Meteorology and Oceanography

The global warming is not uniformly distributed over the Earth. The polar regions are especially sensitive for climate change and the warming in the Arctic is more than twice as fast as for the Earth on average. The effects of this warming are large, with a dramatic loss of sea ice as an example.

The icebreaker Oden on expedition in the Arctic. Photo: Michael Tjernström/MISU/Stockholm University
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