Research group Group Mannervik
We study transcriptional control of embryo development using cutting-edge genomic technologies and advanced Drosophila genetics.
Group description
Creation of different cell types from an identical DNA sequence is one of the most remarkable properties of genomes, and a fundamental question in developmental biology. Control of transcription establishes the gene expression programs that define a cell and directs cell differentiation. It is thereby critical for embryo development. A mechanistic view of transcriptional regulation is not only necessary for recognition of how specific cell states are established and epigenetically maintained, but also for understanding how its misregulation leads to disease. The Drosophila embryo allows us to dissect these mechanisms in vivo by a set of tools that are not readily available elsewhere. Genomic and genetic approaches are used to identify the mechanisms by which tissue-specific gene expression is controlled in vivo.
Group members
Group managers
Mattias Mannervik
Professor
Members
Aleksander Purik
Student
Artem Ilin
Postdoktor
Sergei Pirogov
PhD Student
Hicham Houhou
Postdoktor
Yanzi Xing
PhD student
