Stockholm university

Research group Group Mannervik

We study transcriptional control of embryo development using cutting-edge genomic technologies and advanced Drosophila genetics.

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Photo: Mannervik lab

Group description

Creation of different cell types from an identical DNA sequence is one of the most remarkable properties of genomes, and a fundamental question in developmental biology. Control of transcription establishes the gene expression programs that define a cell and directs cell differentiation. It is thereby critical for embryo development. A mechanistic view of transcriptional regulation is not only necessary for recognition of how specific cell states are established and epigenetically maintained, but also for understanding how its misregulation leads to disease. The Drosophila embryo allows us to dissect these mechanisms in vivo by a set of tools that are not readily available elsewhere. Genomic and genetic approaches are used to identify the mechanisms by which tissue-specific gene expression is controlled in vivo. 

Group members

Group managers

Mattias Mannervik

Professor

Department of Molecular Biosciences, The Wenner-Gren Institute
Mattias Mannervik

Members

Aleksander Purik

Internship

Department of Molecular Biosciences, Wenner-Grens institute

Willemijn Anna Geeske Bout

Student

Department of Molecular Biosciences, The Wenner-Gren Institute

Hicham Houhou

Postdoktor

Department of Molecular Biosciences, The Wenner-Gren Institute

George William Robert Hunt

PhD student

Department of Molecular Biosciences, The Wenner-Gren Institute

Sergei Pirogov

PhD Student

Department of Molecular Biosciences, The Wenner-Gren Institute
Sergei Pirogov

Yanzi Xing

PhD student

Department of Molecular Biosciences, The Wenner-Gren Institute

Research projects

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