Publications Nedergaard

Author Title Year
Jan Nedergaard, Barbara Cannon
UCP1 mRNA does not produce heat 2013
Jan Nedergaard, Barbara Cannon
How brown is brown fat? : It depends where you look 2013
L. Cheung, J. Gertow, O. Werngren,
et al.
Human mediastinal adipose tissue displays certain characteristics of brown fat 2013
Karen Dixen, Astrid L. Basse, Maria Murholm,
et al.
ERR gamma Enhances UCP1 Expression and Fatty Acid Oxidation in Brown Adipocytes 2013
Naja Zenius Jespersen, Therese Juhlin Larsen, Lone Peijs,
et al.
A classical brown adipose tissue mRNA signature partly overlaps with brite in the supraclavicular region of adult humans 2013
Jan Nedergaard, Irina Shabalina
 Mild uncoupling to counteract ROS production : Physiologically relevant or not? 2013
Barbara Cannon, Jan Nedergaard
Cell biology : Neither brown nor white. 2013
Barbara Cannon, Jan Nedergaard
Yes, even human brown fat is on fire! 2013
Valentina Gburcik, William P. Cawthorn, Jan Nedergaard,
et al.
An essential role for Tbx15 in the differentiation of brown and "brite" but not white adipocytes 2012
Majken S. Siersbaek, Anne Loft, Mads M. Aagaard,
et al.
Genome-Wide Profiling of Peroxisome Proliferator-Activated Receptor gamma in Primary Epididymal, Inguinal, and Brown Adipocytes Reveals Depot-Selective Binding Correlated with Gene Expression 2012
Irina G. Shabalina, Jan Nedergaard
Mitochondrial ('mild') uncoupling and ROS production : physiologically relevant or not? 2012
Jan Nedergaard, Barbara Cannon
Brown adipose tissue: development and function 2012
Jan Nedergaard, Tore Bengtsson, Barbara Cannon
New Powers of Brown Fat : Fighting the Metabolic Syndrome 2012
Miranda Nabben, Irina G. Shabalina, Esther Moonen-Kornips,
et al.
Uncoupled respiration, ROS production, acute lipotoxicity and oxidative damage in isolated skeletal muscle mitochondria from UCP3-ablated mice 2012
Barbara Cannon, Jan Nedergaard
Nonshivering thermogenesis and its adequate measurement in metabolic studies 2011
Pernille Keller, Valentina Gburcik, Natasa Petrovic,
et al.
Gene-chip studies of adipogenesis-regulated microRNAs in mouse primary adipocytes and human obesity 2011
Tomas B Walden, Ida R Hansen, James A Timmons,
et al.
Recruited vs. nonrecruited molecular signatures of brown, “brite,” and white adipose tissues 2011
Jan Nedergaard, Tore Bengtsson, Barbara Cannon
Three years with adult human brown adipose tissue. 2011
Joseph D. Bruton, Jan Aydin, Takashi Yamada,
et al.
Increased fatigue resistance linked to Ca(2+)-stimulated mitochondrial biogenesis in muscle fibres of cold-acclimated mice 2010
Charlotte L Mattsson, Emma R Andersson, Jan Nedergaard
Differential involvement of caveolin-1 in brown adipocyte signaling : impaired beta3-adrenergic, but unaffected LPA, PDGF and EGF receptor signaling. 2010
Tomas B Waldén, Natasa Petrovic, Jan Nedergaard
PPARalpha does not suppress muscle-associated gene expression in brown adipocytes but does influence expression of factors that fingerprint the brown adipocyte. 2010
I Dahlman, N Mejhert, K Linder,
et al.
Adipose tissue pathways involved in weight loss of cancer cachexia 2010
Kent Sahlin, Irina G Shabalina, C Mikael Mattsson,
et al.
Ultraendurance exercise increases the production of reactive oxygen species in isolated mitochondria from human skeletal muscle 2010
Barbara Cannon, Jan Nedergaard
Metabolic and angiogenic consequences of the presence or absence of UCP1 2011
Barbara Cannon, Jan Nedergaard
Metabolic consequences of the presence or absence of the thermogenic capacity of brown adipose tissue in mice (and probably in humans) 2010
Barbara Cannon, Jan Nedergaard
Thyroid hormones : igniting brown fat via the brain. 2010
Lise Madsen, Lone M Pedersen, Haldis Haukaas Lillefosse,
et al.
UCP1 induction during recruitment of brown adipocytes in white adipose tissue is dependent on cyclooxygenase activity. 2010
Charlotte L Mattsson, Robert I Csikasz, Irina G Shabalina,
et al.
Caveolin-1-ablated mice survive in cold by nonshivering thermogenesis despite desensitized adrenergic responsiveness 2010
Irina G Shabalina, Mario Ost, Natasa Petrovic,
et al.
Uncoupling protein-1 is not leaky. 2010
Jan Nedergaard, Barbara Cannon
The changed metabolic world with human brown adipose tissue : therapeutic visions 2010
Irina G Shabalina, Joris Hoeks, Tatiana V Kramarova,
et al.
Cold tolerance of UCP1-ablated mice : A skeletal muscle mitochondria switch toward lipid oxidation with marked UCP3 up-regulation not associated with increased basal, fatty acid- or ROS-induced uncoupling or enhanced GDP effects. 2010
Therese E. Holmström, Charlotte L. Mattsson, Yanling Wang,
et al.
Non-transactivational, dual pathways for LPA-induced Erk1/2 activation in primary cultures of brown pre-adipocytes 2010
Natasa Petrovic, Tomas B Walden, Irina G Shabalina,
et al.
Chronic Perixosome Proliferator-activated Receptor gamma (PPARgamma) activation of epididymally derived white adipocyte cultures reveals a population of thermogenically competent, UCP1-containing adipocytes molecularly distinct from classical brown adipocytes. 2009
Barbara Cannon, Jan Nedergaard
Thermogenesis challenges the adipostat hypothesis for body-weight control. 2009
Daniel Edgar, Irina Shabalina, Yolanda Camara,
et al.
Random point mutations with major effects on protein-coding genes are the driving force behind premature aging in mtDNA mutator mice. 2009
Maria Cristina Zingaretti, Francesca Crosta, Alessandra Vitali,
et al.
The presence of UCP1 demonstrates that metabolically active adipose tissue in the neck of adult humans truly represents brown adipose tissue. 2009
Helena M Feldmann, Valeria Golozoubova, Barbara Cannon,
et al.
UCP1 ablation induces obesity and abolishes diet-induced thermogenesis in mice exempt from thermal stress by living at thermoneutrality. 2009
Tomas B Walden, James A Timmons, Pernille Keller,
et al.
Distinct expression of muscle-specific microRNAs (myomirs) in brown adipocytes. 2009
Yuan Xue, Natasa Petrovic, Renhai Cao,
et al.
Hypoxia-independent angiogenesis in adipose tissues during cold acclimation. 2009
Tatiana V. Kramarova, Irina G. Shabalina, Ulf Andersson,
et al.
Mitochondrial ATP synthase levels in brown adipose tissue are governed by the c-Fo subunit P1 isoform 2011
Jan Aydin, Irina G Shabalina, Nicolas Place,
et al.
Nonshivering thermogenesis protects against defective calcium handling in muscle. 2008
Barbara Cannon, Jan Nedergaard
Developmental biology : Neither fat nor flesh. 2008
Therese E. Holmström, Charlotte L. Mattsson, Johanna M. Fälting,
et al.
Differential signalling pathways for EGF versus PDGF activation of Erk1/2 MAP kinase and cell proliferation in brown pre-adipocytes 2008
Irina G Shabalina, Emma C Backlund, Jacob Bar-Tana,
et al.
Within brown-fat cells, UCP1-mediated fatty acid-induced uncoupling is independent of fatty acid metabolism. 2008
Natasa Petrovic, Irina G Shabalina, James A Timmons,
et al.
Thermogenically competent nonadrenergic recruitment in brown preadipocytes by a PPARgamma agonist. 2008
Barbara Cannon, Jan Nedergaard
Studies of thermogenesis and mitochondrial function in adipose tissues. 2008
Tatiana V Kramarova, Hana Antonicka, Josef Houstek,
et al.
A sequence predicted to form a stem-loop is proposed to be required for formation of an RNA-protein complex involving the 3'UTR of beta-subunit F0F1-ATPase mRNA. 2008

 

Jan Nedergaard, Professor

Visiting address:
Svante Arrhenius väg 20C
Room F362

Postal address:
Stockholm University
Department of Molecular Biosciences,
The Wenner-Gren Institute
SE-106 91 Stockholm

Telephone: +46 8 16 4128
Fax: +46 8 15 6756
E-mail: jan.nedergaard@su.se