Publications

Publications Nedergaard

Author Title Year
Alexander W. Fischer, Irina G. Shabalina, Charlotte L. Mattsson,
et al.
UCP1 inhibition in Cidea-overexpressing mice is physiologically counteracted by brown adipose tissue hyperrecruitment 2017
Anastasia V. Kalinovich, Jasper M. A. de Jong, Barbara Cannon,
et al.
UCP1 in adipose tissues: two steps to full browning 2017
Irina G. Shabalina, Mikhail Yu. Vyssokikh, Natalia Gibanova,
et al.
Improved health-span and lifespan in mtDNA mutator mice treated with the mitochondrially targeted antioxidant SkQ1 2017
Katrin Fischer, Henry H. Ruiz, Kevin Jhun,
et al.
Alternatively activated macrophages do not synthesize catecholamines or contribute to adipose tissue adaptive thermogenesis 2017
Jasper M. A. de Jong, René T. F. Wouters, Nathalie Boulet,
et al.
The β3-adrenergic receptor is dispensable for browning of adipose tissues 2017
Jessica M. Olsen, Robert I. Csikasz, Nodi Dehvari,
et al.
β3-Adrenergically induced glucose uptake in brown adipose tissue is independent of UCP1 presence or activity : Mediation through the mTOR pathway 2017
Alexander W. Fischer, Carolin S. Hoefig, Gustavo Abreu-Vieira,
et al.
Leptin Raises Defended Body Temperature without Activating Thermogenesis 2016
Mayte Alvarez-Crespo, Robert I. Csikasz, Noelia Martinez-Sanchez,
et al.
Essential role of UCP1 modulating the central effects of thyroid hormones on energy balance 2016
Irina G. Shabalina, Anastasia V. Kalinovich, Barbara Cannon,
et al.
Metabolically inert perfluorinated fatty acids directly activate uncoupling protein 1 in brown-fat mitochondria 2016
Marie S. Isidor, Sally Winther, Astrid L. Basse,
et al.
An siRNA-based method for efficient silencing of gene expression in mature brown adipocytes 2016
Alexander W. Fischer, Robert I. Csikasz, Gabriella von Essen,
et al.
Reply to letter to the editor : at thermoneutrality, neither the lean nor the obese freeze 2016
Alexander W. Fischer, Robert I. Csikasz, Gabriella von Essen,
et al.
No insulating effect of obesity 2016
Kosaku Shinoda, Ineke H. N. Luijten, Yutaka Hasegawa,
et al.
Genetic and functional characterization of clonally derived adult human brown adipocytes 2015
Gustavo Abreu-Vieira, Carolina E. Hagberg, Kirsty L. Spalding,
et al.
Adrenergically-stimulated blood flow in brown adipose tissue is not dependent on thermogenesis : Regulation of brown adipose tissue blood flow 2015
Irina G. Shabalina, Luise Landreh, Daniel Edgar,
et al.
Leydig cell steroidogenesis unexpectedly escapes mitochondrial dysfunction in prematurely aging mice 2015
Irina G. Shabalina, Tatiana V. Kramarova, Charlotte L. Mattsson,
et al.
The Environmental Pollutants Perfluorooctane Sulfonate and Perfluorooctanoic Acid Upregulate Uncoupling Protein 1 (UCP1) in Brown-Fat Mitochondria Through a UCP1-Dependent Reduction in Food Intake 2015
Jasper M. A. de Jong, Ola Larsson, Barbara Cannon,
et al.
A stringent validation of mouse adipose tissue identity markers 2015
Gustavo Abreu-Vieira, Alexander W. Fischer, Charlotte Mattsson,
et al.
Cidea improves the metabolic profile through expansion of adipose tissue 2015
Jan Nedergaard, Barbara Cannon
The Browning of White Adipose Tissue : Some Burning Issues 2014
Yanling Wang, Masaaki Sato, Yuan Guo,
et al.
Protein kinase A-mediated cell proliferation in brown preadipocytes is independent of Erk1/2, PI3K and mTOR 2014
K. Chechi, Jan Nedergaard, D. Richard
Brown adipose tissue as an anti-obesity tissue in humans 2014
Jakob D. Wikström, Kiana Mahdaviani, Marc Liesa,
et al.
Hormone-induced mitochondrial fission is utilized by brown adipocytes as an amplification pathway for energy expenditure 2014
Ida R. Hansen, Kim M. Jansson, Barbara Cannon,
et al.
Contrasting effects of cold acclimation versus obesogenic diets on chemerin gene expression in brown and brite adipose tissues 2015
Irina G. Shabalina, Marek Vrbacky, Alena Pecinova,
et al.
ROS production in brown adipose tissue mitochondria : The question of UCP1-dependence 2015
Yanling Wang, Johanna M. Fälting, Charlotte L. Mattsson,
et al.
In brown adipocytes, adrenergically induced beta(1)-/beta(3)-(G(s))-, alpha(2)-(G(i))- and alpha(1)-(G(q))-signalling to Erk1/2 activation is not mediated via EGF receptor transactivation 2013
Karen Dixen, Astrid L. Basse, Maria Murholm,
et al.
ERR gamma Enhances UCP1 Expression and Fatty Acid Oxidation in Brown Adipocytes 2013
L. Cheung, J. Gertow, O. Werngren,
et al.
Human mediastinal adipose tissue displays certain characteristics of brown fat 2013
Jan Nedergaard, Barbara Cannon
UCP1 mRNA does not produce heat 2013
Jan Nedergaard, Barbara Cannon
How brown is brown fat? : It depends where you look 2013
Naja Zenius Jespersen, Therese Juhlin Larsen, Lone Peijs,
et al.
A classical brown adipose tissue mRNA signature partly overlaps with brite in the supraclavicular region of adult humans 2013
Irina G. Shabalina, Natasa Petrovic, Jasper M. A. de Jong,
et al.
UCP1 in Brite/Beige Adipose Tissue Mitochondria Is Functionally Thermogenic 2014
Majken S. Siersbaek, Anne Loft, Mads M. Aagaard,
et al.
Genome-Wide Profiling of Peroxisome Proliferator-Activated Receptor gamma in Primary Epididymal, Inguinal, and Brown Adipocytes Reveals Depot-Selective Binding Correlated with Gene Expression 2012
Valentina Gburcik, William P. Cawthorn, Jan Nedergaard,
et al.
An essential role for Tbx15 in the differentiation of brown and "brite" but not white adipocytes 2012
Barbara Cannon, Jan Nedergaard
Cell biology : Neither brown nor white. 2013
Jan Nedergaard, Irina Shabalina
 Mild uncoupling to counteract ROS production : Physiologically relevant or not? 2013
Barbara Cannon, Jan Nedergaard
Yes, even human brown fat is on fire! 2013
Miranda Nabben, Irina G. Shabalina, Esther Moonen-Kornips,
et al.
Uncoupled respiration, ROS production, acute lipotoxicity and oxidative damage in isolated skeletal muscle mitochondria from UCP3-ablated mice 2012
Jan Nedergaard, Barbara Cannon
Brown adipose tissue: development and function 2012
Irina G. Shabalina, Jan Nedergaard
Mitochondrial ('mild') uncoupling and ROS production : physiologically relevant or not? 2012
Jan Nedergaard, Tore Bengtsson, Barbara Cannon
New Powers of Brown Fat : Fighting the Metabolic Syndrome 2012
Barbara Cannon, Jan Nedergaard
Nonshivering thermogenesis and its adequate measurement in metabolic studies 2011
Tomas B Walden, Ida R Hansen, James A Timmons,
et al.
Recruited vs. nonrecruited molecular signatures of brown, “brite,” and white adipose tissues 2011
Pernille Keller, Valentina Gburcik, Natasa Petrovic,
et al.
Gene-chip studies of adipogenesis-regulated microRNAs in mouse primary adipocytes and human obesity 2011
Barbara Cannon, Jan Nedergaard
Metabolic and angiogenic consequences of the presence or absence of UCP1 2011
I Dahlman, N Mejhert, K Linder,
et al.
Adipose tissue pathways involved in weight loss of cancer cachexia 2010
Tomas B Waldén, Natasa Petrovic, Jan Nedergaard
PPARalpha does not suppress muscle-associated gene expression in brown adipocytes but does influence expression of factors that fingerprint the brown adipocyte. 2010
Charlotte L Mattsson, Emma R Andersson, Jan Nedergaard
Differential involvement of caveolin-1 in brown adipocyte signaling : impaired beta3-adrenergic, but unaffected LPA, PDGF and EGF receptor signaling. 2010
Joseph D. Bruton, Jan Aydin, Takashi Yamada,
et al.
Increased fatigue resistance linked to Ca(2+)-stimulated mitochondrial biogenesis in muscle fibres of cold-acclimated mice 2010
Kent Sahlin, Irina G Shabalina, C Mikael Mattsson,
et al.
Ultraendurance exercise increases the production of reactive oxygen species in isolated mitochondria from human skeletal muscle 2010
Irina G Shabalina, Mario Ost, Natasa Petrovic,
et al.
Uncoupling protein-1 is not leaky. 2010
Jan Nedergaard

 

Jan Nedergaard, Professor

Visiting address:
Svante Arrhenius väg 20C
Room F362

Postal address:
Stockholm University
Department of Molecular Biosciences,
The Wenner-Gren Institute
SE-106 91 Stockholm

Telephone: +46 8 16 4128
Fax: +46 8 16 4209
E-mail:jan.nedergaard@su.se

Group members

Bo Carlsson
Irina Shabalina
Ineke Luijten
Anastasia Kalinovich
Natasa Petrovic
Nathalie Boulet
Erik Lindsund

Patricia Reckziegel
Katie Brooks
Vera Jegminat