Paleogenetics
Photo by Love Dalén
This course will provide the latest knowledge on the different processes that have shaped the evolution and distribution of wild organisms and humans during the past 2.6 million years, and how one can use palaeogenetics of ancient remains and sediments to investigate them. These processes include environmental changes such as climatic and sea level fluctuations, as well as biological changes including speciation, hybridization, range dynamics, and extinctions.
We will go through recent case studies such as neanderthal hybdridization, human expansions, and extinction of the woolly mammoth. An overview of other biomolecular methods that currently are used on ancient materials will also be given. The course has a practical component where you will receive training in laboratory analysis of ancient DNA and how to use computational tools to analyze the resulting sequence data.
The course is divided into two parts. The first part comprises the theory and practice of ancient DNA, and also includes practical lab work that is spread out across the course. The second part focuses on the prehistoric evolution of humans and wild and domesticated organisms, and how these have been affected by past environmental changes.
Teaching Format
The format of the course will be a combination of practical laboratory work, computer labs, formal lectures, and independent literature projects.
Learning outcomes
A list of the learning outcomes can be found in the syllabus. Please find the link to the syllabus on the right side of this page.
Assessment
The assessment will be based on written reports, group discussions, and a final written exam.
Examiner
Love Dalén
Email: love.dalen@zoologi.su.se
Lindqvist, Charlotte, and Om P. Rajora, eds. Paleogenomics: Genome-Scale Analysis of Ancient DNA. Springer, 2019. ISBN 978-3-030-04753-5 (Available as E-book Stockholm University).
The Centre for Palaeogenetics is a research center jointly operated by Stockholm University and the Swedish Museum of Natural History. The center focuses on the study of ancient DNA to explore evolutionary history, biodiversity, and past environments. Researchers at the Centre for Palaeogenetics work at the forefront of palaeogenetic methods, contributing to groundbreaking discoveries about humans, animals, and ecosystems of the past.
