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Martin HögbomProfessor in Biochemistry

Research

Structural Biochemistry

Our main area of interest and expertise is how protein structure relates to function, in particular in proteins that utilize redox active metal cofactors or radicals for catalysis. 

A central theme of our research is to obtain structural information of high-valent protein-coordinated metal sites used for extremely challenging chemical reactions. This information is central for the design of novel bioimetic catalysts for green chemistry and energy conversion. We also study the unique respiratory systems in Mycobacteria to characterize their structure and function. Energy metabolism in these pathogens is currently emerging as a promising new drug target.

We use tools such as synchrotron and free-electron laser X-ray crystallography, Cryo-EM, protein design, enzymatic assays and a variety of spectroscopic techniques.

 

 

Group members

Dan Sjöstrand, Researcher

Esra Bozkurt, Postdoc

Kristine Grave, Postdoc

Terezia Kovalova, Postdoc

Rohit Kumar, Postdoc

Soni Sharma, Postdoc

Vivek Srinivas, Postdoc

Niklas Segerström, Research assistant

Riccardo Diamanti, PhD Student

Juliane John, PhD Student

 

Representative Publications

 

 

          Funding

 

Research projects