Publications

Publications Nedergaard

Author Title Year
Paweł Brzęk, Piotr Selewestruk, Julita Sadowska,
et al.
Divergent selection for basal metabolic rate in mice affects the abundance of UCP1 protein : implications for translational studies 2025
Aaron M. Cypess, Barbara Cannon, Jan Nedergaard,
et al.
Emerging debates and resolutions in brown adipose tissue research 2025
Raman Ahluwalia, Ineke H. N. Luijten, Celso Pereira Batista Sousa-Filho,
et al.
The choice of diet is determinative for the manifestation of UCP1-dependent diet-induced thermogenesis 2025
Irina Shabalina, Daniel Edgar, Natalia Gibanova,
et al.
Enhanced ROS Production in Mitochondria from Prematurely Aging mtDNA Mutator Mice 2024
Patrícia Reckziegel, Natasa Petrovic, Barbara Cannon,
et al.
Perfluorooctanoate (PFOA) cell-autonomously promotes thermogenic and adipogenic differentiation of brown and white adipocytes 2024
Line O. Berthelsen, Mikala Skydsgaard, Jan Nedergaard
Adipose Tissues 2024
Gabriella von Essen, Erik Lindsund, Elaina Maldonado,
et al.
Highly recruited brown adipose tissue does not in itself protect against obesity 2023
Victoria S. Davies, Erik Lindsund, Natasa Petrovic,
et al.
Repeated short excursions from thermoneutrality suffice to restructure brown adipose tissue 2023
Jan Nedergaard, Alexander W. Fischer, Barbara Cannon
Leptin as an Antitorpor Hormone : An Explanation for the Increased Metabolic Efficiency and Cold Sensitivity of ob/ob Mice? 2023
Luís Felipe Galvão Valdivia, Érique Castro, Rosangela Aparecida dos Santos Eichler,
et al.
Cold acclimation and pioglitazone combined increase thermogenic capacity of brown and white adipose tissues but this does not translate into higher energy expenditure in mice 2023
Jan Nedergaard, Gabriella von Essen, Barbara Cannon
Brown adipose tissue : can it keep us slim? A discussion of the evidence for and against the existence of diet-induced thermogenesis in mice and men 2023
Yun Gao, Irina G. Shabalina, G. Ruda F. Braz,
et al.
Establishing the potency of N-acyl amino acids versus conventional fatty acids as thermogenic uncouplers in cells and mitochondria from different tissues 2022
Jan Nedergaard, Barbara Cannon
Diet-Induced Thermogenesis : Principles and Pitfalls 2022
Rosemari Otton, Natasa Petrovic, Barbara Cannon,
et al.
On the Validity of Adipogenic Cell Lines as Model Systems for Browning Processes : In Authentic Brown, Brite/Beige, and White Preadipocytes, There is No Cell-Autonomous Thermogenic Recruitment by Green Tea Compounds 2021
Petr Zouhar, Petra Janovska, Sara Stanic,
et al.
A pyrexic effect of FGF21 independent of energy expenditure and UCP1 2021
Nathalie Boulet, Ineke H. N. Luijten, Barbara Cannon,
et al.
Thermogenic recruitment of brown and brite/beige adipose tissues is not obligatorily associated with macrophage accretion or attrition 2021
Barbara Cannon, Jan Nedergaard
A PERKy way to make mitochondrial cristae 2023
Marie S. Isidor, Sally Winther, Lasse K. Markussen,
et al.
Pyruvate kinase M2 represses thermogenic gene expression in brown adipocytes 2020
Francisco García-Carrizo, Barbara Cannon, Jan Nedergaard,
et al.
Regulation of thermogenic capacity in brown and white adipocytes by the prebiotic high-esterified pectin and its postbiotic acetate 2020
Alexander W. Fischer, Barbara Cannon, Jan Nedergaard
Leptin : Is It Thermogenic? 2020
Barbara Cannon, Jasper M. A. de Jong, Alexander W. Fischer,
et al.
Human brown adipose tissue : Classical brown rather than brite/beige? 2020
Petr Zouhar, Gunaj Rakipovski, Muhammad Hamza Bokhari,
et al.
UCP1-independent glucose-lowering effect of leptin in type 1 diabetes : only in conditions of hypoleptinemia 2020
Ineke H. N. Luijten, Barbara Cannon, Jan Nedergaard
Glucocorticoids and Brown Adipose Tissue : Do glucocorticoids really inhibit thermogenesis? 2019
Ineke H. N. Luijten, Helena M. Feldmann, Gabriella von Essen,
et al.
In the absence of UCP1-mediated diet-induced thermogenesis, obesity is augmented even in the obesity-resistant 129S mouse strain 2019
Claudia Dittner, Erik Lindsund, Barbara Cannon,
et al.
At thermoneutrality, acute thyroxine-induced thermogenesis and pyrexia are independent of UCP1 2019
Ineke H. N. Luijten, Katie Brooks, Nathalie Boulet,
et al.
Glucocorticoid-Induced Obesity Develops Independently of UCP1 2019
Jasper M. A. de Jong, Wenfei Sun, Nuno D. Pires,
et al.
Human brown adipose tissue is phenocopied by classical brown adipose tissue in physiologically humanized mice 2020
Alexander W. Fischer, Christian Schlein, Barbara Cannon,
et al.
Intact innervation is essential for diet-induced recruitment of brown adipose tissue 2019
Jan Nedergaard, Yanling Wang, Barbara Cannon
Cell proliferation and apoptosis inhibition : essential processes for recruitment of the full thermogenic capacity-of-brown-adipose-tissue 2019
Alexander W. Fischer, Barbara Cannon, Jan Nedergaard
Optimal housing temperatures for mice to mimic the thermal environment of humans : An experimental study 2018
Jasper M. A. de Jong, Barbara Cannon, Jan Nedergaard
Promotion of lipid storage rather than of thermogenic competence by fetal versus newborn calf serum in primary cultures of brown adipocytes 2018
Carolina E. Hagberg, Qian Li, Maria Kutschke,
et al.
Flow Cytometry of Mouse and Human Adipocytes for the Analysis of Browning and Cellular Heterogeneity 2018
Jasper M. A. de Jong, René T. F. Wouters, Nathalie Boulet,
et al.
The β3-adrenergic receptor is dispensable for browning of adipose tissues 2017
Anastasia V. Kalinovich, Jasper M. A. de Jong, Barbara Cannon,
et al.
UCP1 in adipose tissues: two steps to full browning 2017
Irina G. Shabalina, Mikhail Yu. Vyssokikh, Natalia Gibanova,
et al.
Improved health-span and lifespan in mtDNA mutator mice treated with the mitochondrially targeted antioxidant SkQ1 2017
Jessica M. Olsen, Robert I. Csikasz, Nodi Dehvari,
et al.
β3-Adrenergically induced glucose uptake in brown adipose tissue is independent of UCP1 presence or activity : Mediation through the mTOR pathway 2017
Gabriella von Essen, Erik Lindsund, Barbara Cannon,
et al.
Adaptive facultative diet-induced thermogenesis in wild-type but not in UCP1-ablated mice 2018
Barbara Cannon, Jan Nedergaard
What Ignites UCP1? 2017
Katrin Fischer, Henry H. Ruiz, Kevin Jhun,
et al.
Alternatively activated macrophages do not synthesize catecholamines or contribute to adipose tissue adaptive thermogenesis 2017
Alexander W. Fischer, Irina G. Shabalina, Charlotte L. Mattsson,
et al.
UCP1 inhibition in Cidea-overexpressing mice is physiologically counteracted by brown adipose tissue hyperrecruitment 2017
Alexander W. Fischer, Robert I. Csikasz, Gabriella von Essen,
et al.
Reply to letter to the editor : at thermoneutrality, neither the lean nor the obese freeze 2016
Mayte Alvarez-Crespo, Robert I. Csikasz, Noelia Martinez-Sanchez,
et al.
Essential role of UCP1 modulating the central effects of thyroid hormones on energy balance 2016
Marie S. Isidor, Sally Winther, Astrid L. Basse,
et al.
An siRNA-based method for efficient silencing of gene expression in mature brown adipocytes 2016
Alexander W. Fischer, Carolin S. Hoefig, Gustavo Abreu-Vieira,
et al.
Leptin Raises Defended Body Temperature without Activating Thermogenesis 2016
Alexander W. Fischer, Robert I. Csikasz, Gabriella von Essen,
et al.
No insulating effect of obesity 2016
Irina G. Shabalina, Anastasia V. Kalinovich, Barbara Cannon,
et al.
Metabolically inert perfluorinated fatty acids directly activate uncoupling protein 1 in brown-fat mitochondria 2016
Kosaku Shinoda, Ineke H. N. Luijten, Yutaka Hasegawa,
et al.
Genetic and functional characterization of clonally derived adult human brown adipocytes 2015
Irina G. Shabalina, Luise Landreh, Daniel Edgar,
et al.
Leydig cell steroidogenesis unexpectedly escapes mitochondrial dysfunction in prematurely aging mice 2015
Irina G. Shabalina, Tatiana V. Kramarova, Charlotte L. Mattsson,
et al.
The Environmental Pollutants Perfluorooctane Sulfonate and Perfluorooctanoic Acid Upregulate Uncoupling Protein 1 (UCP1) in Brown-Fat Mitochondria Through a UCP1-Dependent Reduction in Food Intake 2015
Jasper M. A. de Jong, Ola Larsson, Barbara Cannon,
et al.
A stringent validation of mouse adipose tissue identity markers 2015

 

Jan Nedergaard, Professor emeritus

Visiting address:
Svante Arrhenius väg 20C
Room F362

Postal address:
Stockholm University
Department of Molecular Biosciences,
The Wenner-Gren Institute
SE-106 91 Stockholm

Telephone: +46 8 16 4128
E-mail:jan.nedergaard@su.se

Group members

Erik Lindsund
Natasa Petrovic
Irina Shabalina
Naren Qimuge
Jiaping Li
Rudá Glauber Braz
Uzair Ali