To maintain DNA stability and genome integrity in mammalian cells, processes are activated to repair DNA adducts, involving hundreds of proteins which are recruited into complexes that are specific for the type of lesion.
Cancer is one of the major causes of morbidity and mortality in the general population. In developed nations unsuitable diets have been identified as one of the outstanding avoidable detrimental factors.
A number of epidemiological studies have consistently demonstrated the protective effects of fruits and vegetables with respect to several age related diseases. The aim of this project is to investigate the protective action of agents with potential use as functional food constituents with respect to cancer, diabetes and cardiovascular disease.
