Stockholm university
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Research subject Methods for simulations of biological systems

Related research subject

Bioinformatics

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Researchers

Erik Lindahl

Professor of Theoretical Chemistry

Department of Biochemistry and Biophysics
08-16 10 62
Erik Lindahl
erik.lindahl@dbb.su.se
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Research group

Erik Lindahl's research group

Our research is focused on understanding the doors and windows of our cells in the form of membrane proteins in general, and in particular the functions of ion channels and pumps that transport ions to make our nervous system work.

Erik Lindahl
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Research projects

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Membrane proteins are of exceptional importance for transport and signalling in the cell, and pumps and channels in particular are key examples of proteins that adopt different conformational states as part of cycles that define their function.

Research
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Pentameric ligand-gated channels mediate signals across the kingdoms of life and are highly sensitive to modulators such as benzodiazepines or alcohol. Recent advances in cryo-EM have enabled us to identify and obtain structures of several new channels, including new prokaryotic model systems and heteromeric channels in the human nervous system.

Research

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