Cells relay on natively folded proteins to stay alive and misfolded proteins are toxic. We study how molecular chaperones maintain proteins folded even under stressful conditions
Actin polymerization is a key force-generating mechanism behind intracellular transport and cell migration. We study its regulation, focusing on the role of profilin and the profilin:actin complex.
Genetic and molecular characterization of extracellular nutrient-induced signal transduction pathways in fungirequired for proper nitrogen source acquisition.
Chromatin remodeling is required for several nuclear processes, such as transcription, replication and DNA repair. We investigatehow chromatin remodeling affects expression of ribosomal RNA and protein coding genes.
