Stockholm university
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Structure and Dynamics of Biological Membranes

The course provides advanced knowledge of the lipid membrane and its interplay with membrane protein structure and functio

A broad overview of the different types of membrane protein families with an emphasis on transporters, channels, GPCRs and respiratory proteins is covered.

We will discuss how energy is transformed to do work at the molecular level and the role of the lipid bilayer to facilitate this.

Additionally, the course highlights practical methods for working with membrane proteins as well as the most recent advances in membrane protein research, where the determination of structures has led to the understanding of basic mechanisms such as e.g., ion-conductance at the molecular level.

The course is closely associated to the research activities at the Department, where several groups are in the front line at the international level.

  • Course structure

    After completing the course, the student should be able to:

    • Explain the biochemical and physical properties of biological membranes (part 1).
    • Explain the principles of biogenesis and the design of membrane proteins, as well as membrane transport (part 1).
    • Describe a number of techniques that can be used for studying membrane proteins (part 1, part 2).
    • Practically apply theoretical knowledge and conduct experiments in the field of membrane protein biochemistry (part 2).
    • Critically analyze and present scientific data (part 1, part 2).
    • Demonstrate insight into how research in the field of biochemistry is organized and conducted (part 2).

    Modules

    The course consists of the following modules:
    1. Theory, 7.5 hp
    2. Laboratory exercises, 7.5 hp

    Teaching format

    The course consists of lectures, seminars, exercises, projects and laboratory exercises.

    Assessment

    The course is examined as follows:
    Examination of the theory part is done by written exams, written reports and oral presentations.

    Examination of the laboratory part is done by written lab reports.

    Examiner

    David Drew

    E-mail: david.drew@dbb.su.se

  • Contact

    David Drew

    E-mail: david.drew@dbb.su.se

    Chemistry Section & Student Affairs Office