Neurochemistry with Molecular Neurobiology
15 credits cr.
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The human brain contains about 100 billion neurons and it has been estimated that these neurons form close to 10 000 billion contact points (synapses) with each other...
Understanding the brain and the nervous system is one of the most complex challenges for modern science. During this course you dive into the biochemistry of the nervous system and try to understand the nervous system and neurons on a biochemical/molecular level
The course will cover the following:
- Neurotransmitter synthesis
- Metabolic mechanisms at the synapse
- Release and re-uptake/degradation of classical neurotransmitters
- Receptors for neurotransmitters and their ligands, from a chemical-pharmacological point of view
- The relevance of above molecules and their interactions for development of tolerance, supersensitivity and long term potentiation are discussed.
- Aspects of neurochemistry as a basis for neuropharmacology will also be covered.
Theory 7.5 ECTS
Laboratory exercises 6 ECTS
Literature seminar 1.5 ECTS
Lectures (not mandatory but highly recommended)
21 lectures whereof some are mixed with group exercises
Give you a factual basis, will teach new terminology, facts and details
Two small short tests (dugga)
Will give you a chance to get feedback on what you have learned so far
- Short test 1, home assignment
- Short test 2, written exam, may give bonus points on final exam
Laboratory exercises (mandatory)
- Three dry labs
- Two wet labs
Journal club exercises (mandatory)
Will cover how to read and evaluate quality of a research article within neurochemistry with molecular neurobiology field.
- Written exam at the end of the course
- Individual lab reports, to be handed in latest one week after each lab exercise
- Litterature seminar presentation
Associate Professor Anna-Lena Ström
ScheduleThe schedule will be available no later than one month before the start of the course. We do not recommend print-outs as changes can occur. At the start of the course, your department will advise where you can find your schedule during the course.
Note that the course literature can be changed up to two months before the start of the course.
- Lecture hand-outs
- Scientific articles
- Basic Neurochemistry: Principles of molecular, cellular and medical neurobiology Editors ST Brady, GJ Siegel, RW Albers & DL Price. Eighth edition, 2012, Academic Press, ISBN: 978-0-12-374947-5, recommended but not necessary
Associate Professor Anna-Lena StrömChemistry Section & Student Affairs Office