Advanced Organic Chemistry
15 credits cr.
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This course in advanced organic chemistry emphasize on the most important aspects of reactivity within the field of organic synthesis. The students will gain a deeper mechanistic understanding of organic reactions as well as a broader knowledge regarding organic reactivity.
The course focuses on the most important reactions in organic chemistry and provides an in-depth study as well as a broadening of the organic chemical reaction theory. Important areas discussed include everything from useful synthesis methods and reagents to how organic reactions can be controlled to provide the highest possible chemo-, regio- or stereoselectivity.
All reactions are discussed from a mechanistic perspective.
The ability to control the reactivity and the selectivity of a particular transformation is a central pillar in modern synthetic organic chemistry, and these aspects are thoroughly discussed in this course.
In particular, methods for controlling the chemo-, regio- and enantioselectivity are highlighted.
Important specific topics covered in this course include:
- Selective carbonyl reactions
- Oxidations and reductions
- Organometallic reagents
- Pericyclic reactions
- Multi-step synthesis
- Synthesis strategy, protecting group strategies
The course is given over a full semesters which make it possible to combine with the 45 hp Degree project in organic chemistry.
Teaching The teaching consists of lectures, exercises and presentations. Participation in presentations is mandatory.
After completing the course the student should:
- be able to analyze
- explain and solve advanced organic-chemical problems based on a mechanical synthesis methods for producing everything from simple to more complex organic compounds
- be able to predict the stereochemical outcome in stereoselective reactions
- be able to plan multistage syntheses of more complex organic compounds
- be able to read and understand organic chemical primary literature
The teaching consists of lectures, exercises and presentations. Participation in presentations is mandatory.
Written exam at the end of the course.