Stem Cells in Developmental- and Cancer Biology, 15 credits

About the course

The course covers the molecular mechanisms regulating the division and differentiation of stem cells in development and cancer. Mechanisms of cell differentiation and de-differentiation, reprogramming, induction of pluripotent cells, and the signaling pathways controlling these processes will be discussed. Important aspects of stem cell regulation, such as epigenetic changes, the presence of a niche, and asymmetric cell division will be covered. Medical applications, mainly stem cell therapy and consequences of the cancer stem cell concept for cancer treatment, will be discussed. Course period: January - March

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