Structure and Dynamics of Biological Membranes
7 credits cr.
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The course provides advanced knowledge of the lipid membrane and its interplay with membrane protein structure and function.
This course is part of the joint Master’s programme in Molecular techniques in life science, together with KTH and KI. The course is not open for application to students outside of the programme.
A broad overview of the different types of membrane protein families with an emphasis on transporters, channels, GPCRs and respiratory proteins is covered.
We will discuss how energy is transformed to do work at the molecular level and the role of the lipid bilayer to facilitate this.
Additionally, the course highlights practical methods for working with membrane proteins as well as the most recent advances in membrane protein research, where the determination of structures has led to the understanding of basic mechanisms such as e.g., ion-conductance at the molecular level.
The course is closely associated to the research activities at the Department, where several groups are in the front line at the international level.
After completing the course the student should:
- be able to explain the biochemical and physical properties of biological membranes
- be able to explain principles for biogenesis and design of membrane proteins
- be able to explain a number of techniques that can be used for studies of membrane proteins
- be able to explain principles for membrane transport
The teaching consists of lectures, seminars, project work, and demonstrations of laboratory techniques.
ScheduleThe schedule will be available no later than one month before the start of the course. We do not recommend print-outs as changes can occur. At the start of the course, your department will advise where you can find your schedule during the course.