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Comparative Genomics

Today the genome sequence of thousands of organisms is known, including our own genome sequence and that of many closely related species. The course covers bioinformatical methods to analyse genome, basics of how prokaryote and eukaryote genomes are built, the principles of gene prediction and sequence comparisons.

This course is part of the joint master’s programme in Molecular techniques in life science, together with KTH and KI. The course is not open for application to students outside of the programme.

To understand human biology and origins as well as how life in general has evolved it is necessary to compare these genomes. In this course you will learn how to compare genomes using bioinformatic techniques such as phylogeny and orthology prediction as well as other methods to understand the evolution of genes and genomes.

Moreover, you will learn how to do functional annotation of proteins on the genome scale, and how to analyse the interactome.

  • Course structure

    After completing the course, the student is expected to:

    • be able to discuss how different genomes are constructed
    • be able to predict genes in a genome sequence
    • be able to discuss and apply methods for sequence comparisons
    • be able to discuss and apply phylogenetic analysis
    • be able to discuss and apply orthology analysis

  • Schedule

    The schedule will be available no later than one month before the start of the course. We do not recommend print-outs as changes can occur. At the start of the course, your department will advise where you can find your schedule during the course.

  • Course literature

    Note that the course literature can be changed up to two months before the start of the course.

    Suggested:

    Zvelebil, M. J., Baum, J.O. (2007) Understanding Bioinformatics, Garland Science

  • Contact

    Course coordinator and examiner
    Erik Sonnhammer

    Professor

    erik.sonnhammer@dbb.su.se
    Erik
    Chemistry Section & Student Affairs Office
    chemistry@su.se
    08-16 37 09
    Arrhenius laboratory exterior
    • Visiting address

    • Arrhenius laboratory, room M345

    • Svante Arrhenius väg 16 A-D

    • Here you will find:

    • Student administrator

      International coordinator

      Study advisor

      Director of studies

    • Office hours

    • Monday, Tuesday and Wednesday 09.00-11.30 and 12.30-15.00

    • Phone hours

    • Wednesday 10.00-11.30 and 12.30-15.00

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