Regulatory T-cell responses in patients with type I allergies
It is well established that IgE antibodies (Abs) to allergens are the predominant and most likely the only isotype of Abs responsible for inducing type I allergic diseases in humans. However, not all individuals exposed to allergens become allergic and moreover, not all individuals with elevated IgE Abs to exogenous antigens show immediate hypersensitivity reactions to these antigens.