Stockholm university

Research group Group Wäneskog

We study how bacteria and fungi respond and adapt to cytotoxic stress caused by chemicals, microbial toxins, and viral infections by using a combination of custom-designed synthetic biology tools, high-throughput assays, and multi-omics approaches.

Group description

Bacterial and fungal cells are regularly exposed to a variety of toxic chemicals, microbial toxins, and viruses. To survive these potentially lethal threats, microbial cells rely on complex molecular adaptations that enable them to prevent and repair cellular damage and alter essential metabolic processes. Gaining insight into these survival mechanisms is crucial for understanding the adaptability of unicellular organisms. 

By comprehensively mapping how microbes survive and thrive under stress, we aim to uncover weaknesses that could be exploited for therapeutic gain. Thus, our research not only aims to enhance our fundamental understanding of microbial stress responses, but also to guide the development of the next generation of antimicrobial therapies.
 

Group members

Group managers

Marcus Wäneskog

Group leader

Department of Molecular Biosciences, The Wenner-Gren Institute

Research projects

Publications

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