Simultaneous mapping of several different epigenetic landmarks in a single cell
Researchers at Karolinska Institutet had in 2021 developed a technique making possible to examine how different versions of histones bind to the genome in tens of thousands of individual cells.
Breast cancer spread uncovered by new molecular microscopy
Researchers have created a tool that maps how breast cancer grows in previously unseen detail, and highlights how the cells around the tumor may be the key to controlling the spread of disease.
AI will map proteins and increase understanding of how cells work
Artificial intelligence (AI) and deep learning are becoming increasingly important to map the proteins in our cells and how they interact with each other.
Martin Högbom wants to be as good as nature at chemistry
Martin Högbom, professor in biochemistry, Head of the Department of Biochemistry and Biophysics, and Wallenberg Scholar, talks about his research in this video from the Knut och Alice Wallenberg Foundation.
By understanding why certain nerve cells and the muscles they control are resistant to fading in the deadly disease ALS, it is possible to create new possibilities for treatments.
A most dangerous poison can be of great benefit as a drug
Through molecular genealogy, Pål Stenmark (professor of biochemistry) has found a new family of botulinum toxins, where a variant can fight malaria mosquitoes.
A salt transporter linked to hypertension and diabetes
Researchers at Stockholm University shed new light on how transporter-protein exchangers the movement of sodium ions across cell membranes with the movement of protons.
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A new intersectoral and interdisciplinary project between nine Swedish Universities and MAX IV – a Ph.D. programme called PRISMAS – launches in January 2023. The program is dedicated to the UN Sustainable Development Goals and Horizon Europe's essential research and innovation areas. The project will create a connected network of next-generation X-ray experts, enabling various stakeholders to take full advantage of world-leading synchrotron facilities such as MAX IV, while tackling current societal challenges in the same breath.
Researchers at Karolinska Institutet had in 2021 developed a technique making possible to examine how different versions of histones bind to the genome in tens of thousands of individual cells. Now the same team developed a new technology allowing simultaneous probing of several different histone marks in one individual cell and in thousands of cells at the same time. This new method allows to investigate in much greater detail how cells in the mouse brain acquire unique properties and specialize. The study is published in the journal Nature Biotechnology.
Children diagnosed with brain cancer often die within a year of their initial diagnosis because there are no effective treatments for this rare form of cancer. But by visualizing the cancer cells, researchers have now gained a better understanding of what the tumors look like. The hope is that it will lead to new treatment methods. This is shown by a study with researchers at, among others, Stockholm University and SciLifeLab, recently published in Nature Genetics.
Researchers have created a tool that maps how breast cancer grows in previously unseen detail, and highlights how the cells around the tumor may be the key to controlling the spread of disease